Department of Microbiology Osmania University, Hyderabad, 500 007 India.
Indian J Microbiol. 2008 Sep;48(3):397-400. doi: 10.1007/s12088-008-0047-9. Epub 2009 Mar 25.
Saccharomyces cerevisiae which cannot utilize lysine as a sole nitrogen source is shown to metabolize a Lysine 3 Cr(3+) (1:1) complex synthesized, as a combined nitrogen and carbon source. It induces rapid uptake of lysine and prevents loss of viability, in contrast with free lysine. That complexation with trivalent chromium has the effect of profoundly influencing intracellular distribution and metabolism of the liganded amino acid is demonstrated.
酿酒酵母不能将赖氨酸作为唯一氮源,而现在研究表明其可以代谢合成的赖氨酸-3 铬(3+)(1:1)复合物作为氮碳源。与游离赖氨酸相比,它可以诱导赖氨酸的快速摄取并防止生存能力丧失。研究表明,三价铬的络合作用会显著影响配位氨基酸在细胞内的分布和代谢。