Mukai K, Rosai J, Hallaway B E
Am J Surg Pathol. 1979 Aug;3(4):373-6. doi: 10.1097/00000478-197908000-00008.
Using an immunoperoxidase method, myoglobin is localized in the cytoplasm of normal and neoplastic human skeletal muscle. The staining intensity is variable in individual cells. This can be explained by the variable concentration of myoglobin in the different fiber types of normal muscle or the different degree of differentiation in neoplastic muscle cells, respectively. A potential application of this method in tumor pathology is discussed in connection with myoglobin as a tissue-specific marker for skeletal muscle neoplasms.
采用免疫过氧化物酶法，肌红蛋白定位于正常和肿瘤性人类骨骼肌的细胞质中。单个细胞中的染色强度各不相同。这分别可以通过正常肌肉不同纤维类型中肌红蛋白浓度的差异或肿瘤性肌细胞中不同的分化程度来解释。结合肌红蛋白作为骨骼肌肿瘤的组织特异性标志物，讨论了该方法在肿瘤病理学中的潜在应用。
