遗传学与龋齿：展望。
Genetics and caries: prospects.
机构信息
Departments of Oral Biology and Pediatric Dentistry, and Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
出版信息
Braz Oral Res. 2012;26 Suppl 1(Suppl 1):7-9. doi: 10.1590/s1806-83242012000700002.
Caries remains the most prevalent non-contagious infectious disease in humans. It is clear that the current approaches to decrease the prevalence of caries in human populations, including water fluoridation and school-based programs, are not enough to protect everyone. The scientific community has suggested the need for innovative work in a number of areas in cariology, encompassing disease etiology, epidemiology, definition, prevention, and treatment. We have pioneered the work on genetic studies to identify genes and genetic markers of diagnostic, prognostic, and therapeutic value. This paper summarizes a presentation that elaborated on these initial findings.
龋齿仍然是人类最普遍的非传染性传染病。显然，目前减少人群龋齿患病率的方法，包括水氟化和学校为基础的项目，还不足以保护每个人。科学界建议在龋病学的多个领域开展创新性工作，包括疾病病因学、流行病学、定义、预防和治疗。我们率先开展了基因研究，以确定具有诊断、预后和治疗价值的基因和遗传标记。本文总结了对这些初步发现的阐述。
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