Cummings K M, Markello S J, Mahoney M, Bhargava A K, McElroy P D, Marshall J R
Department of Cancer Control and Epidemiology, Rowell Park Cancer Institute, Buffalo, New York.
Arch Environ Health. 1990 Mar-Apr;45(2):74-9. doi: 10.1080/00039896.1990.9935929.
Reports of recent exposure to environmental tobacco smoke (ETS) and urinary cotinine levels were obtained on 663 never- and ex-smokers who attended a cancer screening clinic in Buffalo, New York, in 1986. Study objectives included determining the prevalence of exposure to ETS using urinary cotinine and identifying questionnaire exposure measures predictive of cotinine. Findings demonstrate that exposure to environmental tobacco smoke is extremely prevalent, even among those not living with a smoker. A total of 76% of subjects reported exposure to ETS in the 4 d preceding the interview. The most frequently mentioned sources of exposure were at work (28%) and at home (27%). Cotinine was found in the urine of 91% of subjects. Cotinine values increased significantly with the number of exposures reported. Among the different questionnaire measures of exposure that were evaluated, the single best predictor of cotinine was the number of friends and family members seen regularly by the subject who smoke.
1986年,在纽约州布法罗市一家癌症筛查诊所就诊的663名从不吸烟和曾经吸烟的人提供了近期接触环境烟草烟雾(ETS)的报告及尿中可替宁水平。研究目标包括使用尿中可替宁确定ETS暴露的患病率,并确定可预测可替宁的问卷暴露测量方法。研究结果表明,即使在那些没有与吸烟者同住的人中,接触环境烟草烟雾也极为普遍。共有76%的受试者报告在访谈前4天接触过ETS。最常提到的接触源是工作场所(28%)和家庭(27%)。91%的受试者尿液中检测到可替宁。可替宁值随着报告的接触次数显著增加。在评估的不同问卷暴露测量方法中,可替宁的最佳单一预测指标是受试者经常见到的吸烟朋友和家庭成员的数量。