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通过离子束辅助沉积在超大钻孔牙槽窝中涂覆磷酸钙的种植体上的骨附着：犬的组织学和组织计量学分析

Bone apposition on implants coated with calcium phosphate by ion beam assisted deposition in oversized drilled sockets: a histologic and histometric analysis in dogs.

作者信息

Kim Min-Soo, Jung Ui-Won, Kim Sungtae, Lee Jung-Seok, Lee In-Seop, Choi Seong-Ho

机构信息

Department of Periodontology, Research Institute for Periodontal Regeneration, Yonsei University College of Dentistry, Seoul, Korea.

出版信息

J Periodontal Implant Sci. 2013 Feb;43(1):18-23. doi: 10.5051/jpis.2013.43.1.18. Epub 2013 Feb 28.

DOI:10.5051/jpis.2013.43.1.18
PMID:23507657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3596629/
Abstract

PURPOSE

The purpose of this study was to evaluate the osseointegration of calcium phosphate (CaP)-coated implants by ion beam assisted deposition with a lack of primary stability.

METHODS

A total of 20 CaP-coated implants were bilaterally placed in the mandible of five dogs. In the rotational implant group, the implants were inserted in oversized drilled sockets without mechanical engagement, while the conventional surgical protocol was followed in the control group. Each group was allowed to heal for 4 and 8 weeks. The bone-to-implant contact (BIC, %) was measured by a histometric analysis.

RESULTS

All of the implants were well-maintained and healing was uneventful. In the histologic observation, all of the implants tested were successfully osseointegrated with a high level of BIC at both observation intervals. There was no significant difference in BIC among any of the groups.

CONCLUSIONS

Within the limitation of this study, successful osseointegration of CaP-coated implants could be achieved in unfavorable conditions without primary stability.

摘要

目的

本研究旨在评估通过离子束辅助沉积制备的缺乏初期稳定性的磷酸钙（CaP）涂层种植体的骨整合情况。

方法

将总共20枚CaP涂层种植体双侧植入5只犬的下颌骨。在旋转种植体组中，种植体植入超尺寸钻孔牙槽窝中，无机械固位，而对照组遵循传统手术方案。每组均给予4周和8周的愈合时间。通过组织计量学分析测量骨与种植体的接触率（BIC，%）。

结果

所有种植体均保持良好，愈合过程顺利。在组织学观察中，所有测试种植体在两个观察时间点均成功实现骨整合，且BIC水平较高。各实验组之间BIC无显著差异。

结论

在本研究的局限性范围内，CaP涂层种植体在缺乏初期稳定性的不利条件下也能成功实现骨整合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/cb888dc92451/jpis-43-18-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/794b40e9ee85/jpis-43-18-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/c295cea2d7d7/jpis-43-18-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/922c10c4eb05/jpis-43-18-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/54eef690aff5/jpis-43-18-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/c3de72e1bfa8/jpis-43-18-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/cb888dc92451/jpis-43-18-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/794b40e9ee85/jpis-43-18-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/c295cea2d7d7/jpis-43-18-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/922c10c4eb05/jpis-43-18-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/54eef690aff5/jpis-43-18-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/c3de72e1bfa8/jpis-43-18-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6776/3596629/cb888dc92451/jpis-43-18-g006.jpg

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