来自菠萝蜜树枝条的新酚类化合物。
New phenolic compounds from the twigs of Artocarpus heterophyllus.
作者信息
Di X, Wang S, Wang B, Liu Y, Yuan H, Lou H, Wang X
机构信息
Department of Natural Product Chemistry, Shandong University, Ji'nan, Shandong, China.
出版信息
Drug Discov Ther. 2013 Feb;7(1):24-8. doi: 10.5582/ddt.2013.v7.1.24.
Two new chalcones, artocarpusins A and B (1 and 2), one new flavone, artocarpusin C (3), one new 2-arylbenzofuran derivative, artocarstilene A (4), and 15 flavonoids were isolated from the twigs of Artocarpus heterophyllus. Their structures were established on the basis of extensive spectroscopic analysis. Compounds 9 and 16 showed moderate inhibitory activity on the proliferation of the PC-3 and H460 cell lines.
从菠萝蜜的嫩枝中分离出两种新的查耳酮，波罗蜜素A和B（1和2），一种新的黄酮，波罗蜜素C（3），一种新的2-芳基苯并呋喃衍生物，波罗蜜烯A（4），以及15种黄酮类化合物。它们的结构通过广泛的光谱分析得以确定。化合物9和16对PC-3和H460细胞系的增殖表现出中等抑制活性。
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