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婴儿气质与儿童精神疾病:纵向研究

Infant temperament and childhood psychiatric disorder: longitudinal study.

作者信息

Sayal K, Heron J, Maughan B, Rowe R, Ramchandani P

机构信息

Division of Psychiatry and Institute of Mental Health, University of Nottingham, Nottingham, UK.

出版信息

Child Care Health Dev. 2014 Mar;40(2):292-7. doi: 10.1111/cch.12054. Epub 2013 Apr 3.

Abstract

BACKGROUND

Temperamental characteristics emerge early in life and can shape children's development, adjustment and behaviour. We aimed to investigate the association between early infant temperament and later childhood psychiatric disorder in a community sample.

METHODS

This prospective, population-based study used data from the Avon Longitudinal Study of Parents and Children (ALSPAC). In a sample of 7318 children, we investigated whether temperamental characteristics assessed at the ages of 6 months and 24 months are associated with an independent diagnosis of psychiatric disorder ascertained at age 7 years.

RESULTS

After adjusting for confounders, temperamental characteristics assessed at 6 and 24 months of age were associated with psychiatric disorder at age 7 years. In particular, intensity of emotional reaction at age 6 months was associated with later disorder (adjusted odds ratio = 1.56; 95% confidence interval 1.19, 2.04; P = 0.002). These associations were stronger in girls and in those children with high levels of intensity at both 6 and 24 months of age.

CONCLUSIONS

Temperamental characteristics involving high levels of emotional intensity within the first year of life are longitudinally associated with psychiatric disorder in mid-childhood, suggesting that the roots of psychiatric disorder may, in some cases, lie very early in life.

摘要

背景

气质特征在生命早期出现,并可塑造儿童的发育、适应能力和行为。我们旨在调查社区样本中早期婴儿气质与儿童期后期精神障碍之间的关联。

方法

这项基于人群的前瞻性研究使用了阿冯父母与儿童纵向研究(ALSPAC)的数据。在7318名儿童的样本中,我们调查了6个月和24个月时评估的气质特征是否与7岁时确诊的精神障碍独立诊断相关。

结果

在调整混杂因素后,6个月和24个月时评估的气质特征与7岁时的精神障碍相关。特别是,6个月时的情绪反应强度与后期障碍相关(调整后的优势比 = 1.56;95%置信区间1.19,2.04;P = 0.002)。这些关联在女孩以及6个月和24个月时强度水平都很高的儿童中更强。

结论

生命第一年中情绪强度较高的气质特征与童年中期的精神障碍存在纵向关联,这表明精神障碍的根源在某些情况下可能早在生命早期就已存在。

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