在常规监测中检测到宋内志贺菌中的新德里金属β-内酰胺酶（由 blaNDM-1 编码）。
Detection of New Delhi metallo-β-lactamase (encoded by blaNDM-1) in Acinetobacter schindleri during routine surveillance.
机构信息
Multidrug-resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
出版信息
J Clin Microbiol. 2013 Jun;51(6):1942-4. doi: 10.1128/JCM.00281-13. Epub 2013 Apr 3.
Abstract
A carbapenem-resistant Alcaligenes faecalis strain was isolated from a surveillance swab of a service member injured in Afghanistan. The isolate was positive for bla(NDM) by real-time PCR. Species identification was reevaluated on three identification systems but was inconclusive. Genome sequencing indicated that the closest relative was Acinetobacter schindleri and that bla(NDM-1) was carried on a plasmid that shared >99% identity with one identified in an Acinetobacter lwoffii isolate. The isolate also carried a novel chromosomally encoded class D oxacillinase.
摘要
从在阿富汗受伤的一名军人的监测拭子中分离出一株耐碳青霉烯类的粪产碱杆菌。该分离株经实时 PCR 检测 bla(NDM)呈阳性。通过三种鉴定系统重新评估了种属鉴定，但结果不确定。基因组测序表明，最接近的亲缘关系是琼氏不动杆菌，bla(NDM-1)位于质粒上，该质粒与在一株鲍曼不动杆菌分离株中发现的质粒具有 >99%的同一性。该分离株还携带一种新型的染色体编码的 D 类头孢菌素酶。
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