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Analgesic and anti-inflammatory activities of Passiflora foetida L.西番莲的镇痛和抗炎活性
Asian Pac J Trop Med. 2011 Aug;4(8):600-3. doi: 10.1016/S1995-7645(11)60155-7.
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Anti-inflammatory activity of Premna corymbosa (Burm.f.) Rottl. & Willd. leaves extracts in Wistar albino rats.贯叶连翘叶提取物对 Wistar 白化大鼠的抗炎活性。
Asian Pac J Trop Med. 2011 Jul;4(7):510-3. doi: 10.1016/S1995-7645(11)60136-3.
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Antinociceptive and anti-inflammatory activities of crude extracts of Ipomoea involucrata leaves in mice and rats.翻白草叶的粗提物在小鼠和大鼠体内的镇痛和抗炎活性。
Asian Pac J Trop Med. 2011 Feb;4(2):121-4. doi: 10.1016/S1995-7645(11)60050-3.
4
neo-Clerodane diterpenoids from Ajuga bracteosa.Ajuga bracteosa 中的新 clerodane 二萜。
J Nat Prod. 2011 May 27;74(5):1036-41. doi: 10.1021/np100929u. Epub 2011 May 3.
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Morning symptoms in rheumatoid arthritis: a defining characteristic and marker of active disease.类风湿关节炎的晨僵症状：活动性疾病的一个决定性特征和标志物。
Scand J Rheumatol Suppl. 2011;125:1-5. doi: 10.3109/03009742.2011.566433.
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Effects of honey on inflammation and nitric oxide production in Wistar rats.蜂蜜对Wistar大鼠炎症和一氧化氮生成的影响。
Zhong Xi Yi Jie He Xue Bao. 2011 Apr;9(4):447-52. doi: 10.3736/jcim20110415.
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Screening of antiplasmodial efficacy of Ajuga bracteosa Wall ex. Benth.阿育魏实（白花丹科）抗疟原虫活性筛选
Parasitol Res. 2011 Apr;108(4):801-5. doi: 10.1007/s00436-011-2250-6. Epub 2011 Jan 25.
8
Anti-inflammatory effect of Ajuga bracteosa Wall Ex Benth. mediated through cyclooxygenase (COX) inhibition.筋骨草通过抑制环氧化酶（COX）发挥抗炎作用。
J Ethnopharmacol. 2011 Jan 27;133(2):928-30. doi: 10.1016/j.jep.2010.11.003. Epub 2010 Nov 10.
9
Evaluation of the disease modifying activity of Colchicum luteum Baker in experimental arthritis.评价秋水仙碱在实验性关节炎中的疾病修饰作用。
J Ethnopharmacol. 2011 Jan 27;133(2):303-7. doi: 10.1016/j.jep.2010.09.027. Epub 2010 Oct 20.
10
Antiplasmodial activity of Ajuga bracteosa against Plasmodium berghei infected BALB/c mice.荭草对伯氏疟原虫感染 BALB/c 小鼠的抗疟原虫活性。
Indian J Med Res. 2010 Mar;131:440-4.

筋骨草对白化病大鼠急慢性关节炎模型的抗关节炎作用。

Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats.

作者信息

Kaithwas Gaurav, Gautam Raju, Jachak Sanjay M, Saklani Arvind

机构信息

Department of Pharmaceutical Sciences, Assam University, Silchar-788 011, Assam, India.

出版信息

Asian Pac J Trop Biomed. 2012 Mar;2(3):185-8. doi: 10.1016/S2221-1691(12)60039-2.

DOI:10.1016/S2221-1691(12)60039-2
PMID:23569895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3609278/
Abstract

OBJECTIVE

To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats.

METHODS

The antiarthritic activity of 70% ethanolic extract of Ajuga bracteosa (EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant (CFA)-induced chronic immunological arthritis in albino rats.

RESULTS

EEAB showed a significant (P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis. EEAB exhibited better antiarthritic activity than the standard aspirin.

CONCLUSIONS

EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.

摘要

目的

使用白化大鼠评估苞片筋骨草的抗关节炎活性。

方法

评估苞片筋骨草70%乙醇提取物（EEAB）对白化大鼠由松节油和甲醛诱导的急性非免疫性关节炎以及由完全弗氏佐剂（CFA）诱导的慢性免疫性关节炎的抗关节炎活性。

结果

EEAB对急性和慢性关节炎模型均显示出显著（P<0.05）且剂量依赖性的抑制作用。EEAB表现出比标准阿司匹林更好的抗关节炎活性。

结论

EEAB对急性和慢性关节炎均表现出显著且有前景的抗关节炎活性，支持了苞片筋骨草在治疗风湿和其他炎症性疾病方面的传统用途。