Clinic of Neurology, Medical University, Anichstr. 35, 6020 Innsbruck, Austria.
J Neurol. 2013 Aug;260(8):2066-72. doi: 10.1007/s00415-013-6929-8. Epub 2013 May 7.
Executive dysfunction (ED) is a frequent consequence of neurological disorders, such as stroke, trauma or dementia, but also appears in normal aging. We developed a German version of the Frontal Assessment Battery (FAB-D), a short test which has previously been developed (Dubois et al., Neurology 55:1621-1626, 2000) to detect ED during bedside screening. A sample of 401 cognitively intact subjects aged 50-95 was tested with the FAB-D and several neuropsychological tests tapping executive functions, memory and calculation abilities. Aim of the study was to receive normative data for different age and educational groups, and to learn which tests predict performance on the FAB-D. We found clear effects of age and education; furthermore, FAB-D performance was predicted by other tests of executive functioning, but also by calculation and memory abilities. The present study reports data of healthy individuals and may be useful for comparing patients' performance with a normative sample.
执行功能障碍（ED）是中风、创伤或痴呆等神经障碍的常见后果，但也出现在正常衰老中。我们开发了一种德语版的额叶评估量表（FAB-D），这是一种简短的测试，之前已经开发出来（Dubois 等人，神经病学 55:1621-1626, 2000），用于在床边筛查中检测 ED。我们对 401 名认知正常的 50-95 岁受试者进行了 FAB-D 测试和几项测试执行功能、记忆和计算能力的神经心理学测试。研究的目的是为不同年龄和教育群体提供规范数据，并了解哪些测试可以预测 FAB-D 的表现。我们发现年龄和教育有明显的影响；此外，FAB-D 的表现还可以通过其他执行功能测试以及计算和记忆能力来预测。本研究报告了健康个体的数据，对于将患者的表现与规范样本进行比较可能很有用。
