Russell R G, Sarmiento J I, Fox J, Panigrahi P
Division of Animal Medicine, School of Medicine, University of Washington, Seattle 98195.
Infect Immun. 1990 Jul;58(7):2149-55. doi: 10.1128/iai.58.7.2149-2155.1990.
A prospective bacteriologic study of 18 infant pig-tailed macaques (Macaca nemestrina) housed in a nursery facility in which Campylobacter spp. are endemic was undertaken to determine the epidemiology of infection and reinfection. The isolates of Campylobacter jejuni and C. coli cultured from 8 of the 18 infants were characterized by serotyping, DNA hybridization, and polyacrylamide gel electrophoresis protein profiles. The chronology of infection was indicative of multiple reinfections with different strains of C. jejuni and C. coli during the 12-month study of each infant. The duration of infection with a particular strain was 3 to 4 weeks. Infants were also infected with nalidixic acid-resistant campylobacters. These observations indicated that long-term infections under endemic conditions are caused by continual reinfection. C. jejuni or C. coli infection correlated with diarrhea in 5 of the 18 infants at 1 to 4 months of age.
对18只饲养在弯曲杆菌属流行的保育设施中的幼年猪尾猕猴（食蟹猴）进行了一项前瞻性细菌学研究，以确定感染和再感染的流行病学情况。从18只幼猴中的8只培养出的空肠弯曲菌和结肠弯曲菌分离株，通过血清分型、DNA杂交和聚丙烯酰胺凝胶电泳蛋白谱进行了鉴定。在对每只幼猴进行的12个月研究中，感染的时间顺序表明存在多次不同菌株的空肠弯曲菌和结肠弯曲菌再感染。特定菌株的感染持续时间为3至4周。幼猴还感染了耐萘啶酸的弯曲杆菌。这些观察结果表明，在流行条件下的长期感染是由持续再感染引起的。在1至4个月大的18只幼猴中，有5只的空肠弯曲菌或结肠弯曲菌感染与腹泻相关。
