Suppr超能文献

莱姆病与皮肤

Lyme borreliosis and skin.

作者信息

Vasudevan Biju, Chatterjee Manas

机构信息

Department of Dermatology, Command Hospital, Pune, Maharashtra, India.

出版信息

Indian J Dermatol. 2013 May;58(3):167-74. doi: 10.4103/0019-5154.110822.

Abstract

Lyme disease is a multisystem illness which is caused by the strains of spirochete Borrelia burgdorferi sensu lato and transmitted by the tick, Ixodes. Though very commonly reported from the temperate regions of the world, the incidence has increased worldwide due to increasing travel and changing habitats of the vector. Few cases have been reported from the Indian subcontinent too. Skin manifestations are the earliest to occur, and diagnosing these lesions followed by appropriate treatment, can prevent complications of the disease, which are mainly neurological. The three main dermatological manifestations are erythema chronicum migrans, borrelial lymphocytoma and acrodermatitis chronica atrophicans. Many other dermatological conditions including morphea, lichen sclerosus and lately B cell lymphoma, have been attributed to the disease. Immunofluorescence and polymerase reaction tests have been developed to overcome the problems for diagnosis. Culture methods are also used for diagnosis. Treatment with Doxycycline is the mainstay of management, though prevention is of utmost importance. Vaccines against the condition are still not very successful. Hence, the importance of recognising the cutaneous manifestations early, to prevent systemic complications which can occur if left untreated, can be understood. This review highlights the cutaneous manifestations of Lyme borreliosis and its management.

摘要

莱姆病是一种多系统疾病,由疏螺旋体伯氏疏螺旋体狭义亚种引起,通过蜱虫(硬蜱属)传播。尽管在世界温带地区报道非常普遍,但由于旅行增加和媒介栖息地变化,全球发病率有所上升。印度次大陆也报告了少数病例。皮肤表现是最早出现的,诊断这些病变并随后进行适当治疗,可以预防该疾病的并发症,主要是神经系统并发症。三种主要的皮肤表现是慢性游走性红斑、疏螺旋体淋巴细胞瘤和慢性萎缩性肢端皮炎。许多其他皮肤病,包括硬斑病、硬化萎缩性苔藓以及最近的B细胞淋巴瘤,都被认为与该疾病有关。已经开发了免疫荧光和聚合酶反应测试来克服诊断问题。培养方法也用于诊断。多西环素治疗是主要的治疗方法,尽管预防至关重要。针对这种疾病的疫苗仍然不是很成功。因此,可以理解早期识别皮肤表现以预防如果不治疗可能发生的全身并发症的重要性。这篇综述强调了莱姆病螺旋体病的皮肤表现及其管理。

相似文献

1
Lyme borreliosis and skin.莱姆病与皮肤
Indian J Dermatol. 2013 May;58(3):167-74. doi: 10.4103/0019-5154.110822.
2
Skin manifestations of lyme borreliosis: diagnosis and management.莱姆病的皮肤表现:诊断与管理
Am J Clin Dermatol. 2008;9(6):355-68. doi: 10.2165/0128071-200809060-00002.
3
Skin Changes in Suspected Lyme Disease.疑似莱姆病的皮肤变化。
Acta Dermatovenerol Croat. 2023 Dec;31(4):225-228.
4
Cutaneous manifestations of Lyme borreliosis.莱姆病的皮肤表现
Infection. 1991 Jul-Aug;19(4):284-6. doi: 10.1007/BF01644968.
6
Diagnosis of Lyme disease based on dermatologic manifestations.基于皮肤表现诊断莱姆病。
Ann Intern Med. 1991 Mar 15;114(6):490-8. doi: 10.7326/0003-4819-114-6-490.
8
[Dermatological aspects of Lyme borreliosis].莱姆病的皮肤学表现
Med Mal Infect. 2007 Jul-Aug;37(7-8):540-7. doi: 10.1016/j.medmal.2006.01.013. Epub 2007 Mar 27.

引用本文的文献

2
Bridging the gap: Insights in the immunopathology of Lyme borreliosis.弥合差距:莱姆病免疫病理学的见解
Eur J Immunol. 2024 Dec;54(12):e2451063. doi: 10.1002/eji.202451063. Epub 2024 Oct 13.
3
Lyme Neuroborreliosis in the Context of Dementia Syndromes.痴呆综合征背景下的莱姆病神经疏螺旋体病
Cureus. 2024 Aug 17;16(8):e67057. doi: 10.7759/cureus.67057. eCollection 2024 Aug.
5
Cutaneous Lyme Disease in a Child in Urban Bangalore.班加罗尔市区一名儿童的皮肤型莱姆病
Indian Dermatol Online J. 2023 Aug 15;14(5):698-699. doi: 10.4103/idoj.idoj_401_22. eCollection 2023 Sep-Oct.
6
Lyme Disease: An Overview.莱姆病概述
Indian Dermatol Online J. 2023 Feb 23;14(5):594-604. doi: 10.4103/idoj.idoj_418_22. eCollection 2023 Sep-Oct.
7
Immunologic and nonimmunologic sclerodermal skin conditions - review.免疫性和非免疫性硬皮病皮肤状况——综述。
Front Immunol. 2023 Jul 12;14:1180221. doi: 10.3389/fimmu.2023.1180221. eCollection 2023.
9
Dog tick (Rhipecephalus) causing Lyme disease in an adult human.导致成年人类患莱姆病的犬蜱(璃眼蜱属)
J Family Med Prim Care. 2022 Aug;11(8):4824-4826. doi: 10.4103/jfmpc.jfmpc_33_22. Epub 2022 Aug 30.
10

本文引用的文献

1
Seroprevalence of Borrelia burgdorferi in North Eastern India.印度东北部伯氏疏螺旋体的血清阳性率
Med J Armed Forces India. 2008 Jan;64(1):26-8. doi: 10.1016/S0377-1237(08)80140-2. Epub 2011 Jul 21.
2
Extragenital lichen sclerosus with aetiological link to Borrelia.与伯氏疏螺旋体存在病因学关联的生殖器外硬化性苔藓。
Med J Armed Forces India. 2011 Oct;67(4):370-3. doi: 10.1016/S0377-1237(11)60089-0. Epub 2011 Oct 22.
7
Lyme arthritis: current concepts and a change in paradigm.莱姆关节炎:当前概念与范式转变
Clin Vaccine Immunol. 2008 Jan;15(1):21-34. doi: 10.1128/CVI.00330-07. Epub 2007 Nov 14.
10
Dermatoses from ticks.蜱传播的皮肤病
J Am Acad Dermatol. 2003 Sep;49(3):363-92; quiz 393-6. doi: 10.1067/s0190-9622(03)01868-1.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验