Shanks N, Griffiths J, Zalcman S, Zacharko R M, Anisman H
Department of Psychology, Carleton University, Ottawa, Ontario, Canada.
Pharmacol Biochem Behav. 1990 Jul;36(3):515-9. doi: 10.1016/0091-3057(90)90249-h.
Exposure to acute inescapable footshock provoked marked increases of plasma corticosterone concentrations in six strains of mice (A/J, Balb/cByJ, C57BL/6J, C3H/HeJ, DBA/2J and CD-1). However, the magnitude of the increase, as well as the time required for corticosterone to return to control values, varied appreciably across strains. Moreover, it appeared that the strain-specific corticoid increases ordinarily observed after acute shock were also evidence following a chronic stressor regimen. The data were related to previously observed strain differences in stressor-induced alterations of brain norepinephrine, dopamine and serotonin, as well as variations in performance in several behavioral paradigms.
