Smith Nick, Masters James, Jensen Cyrus, Khan Almas, Sprowson Andrew
Department of Trauma and Orthopaedics, University Hospitals Coventry and Warwickshire, Coventry, UK,
Eur Spine J. 2013 Nov;22(11):2458-65. doi: 10.1007/s00586-013-2848-8. Epub 2013 Jun 23.
Systematic review.
To search and analyse randomised controlled trials (RCTs) published since the Cochrane review by Gibson and Waddell (2007) comparing microendoscopic discectomy (MED) with open discectomy (OD) or microdiscectomy (MD) and to assess whether MED improves patient-reported outcomes. Discectomy for symptomatic herniated lumbar discs is an effective operative treatment. A number of operative techniques exist including OD, MD, and MED. A 2007 Cochrane review identified OD as an effective treatment for symptom improvement, and found sufficient evidence for MD. However, evidence for MED was lacking.
A systematic review of Medline and Embase was carried out. Aiming to identify RCTs carried out after 2007, which compared OD with MD and MED which reported the Oswestry disability index (ODI) as an outcome.
Four RCTs were identified. None of the studies found a significant difference in the ODI scores between study groups at any time point. Three studies compared MED to OD and one compared OD, MD, and MED. The largest study reported an increased number of severe complications in the MED group.
There is some evidence to suggest that MED performed by surgeons skilled in the technique in tertiary referral centres is as effective as OD.
系统评价。
检索并分析自吉布森和沃德尔(2007年)进行Cochrane综述以来发表的比较显微内镜下椎间盘切除术(MED)与开放式椎间盘切除术(OD)或显微椎间盘切除术(MD)的随机对照试验(RCT),并评估MED是否能改善患者报告的结局。对于有症状的腰椎间盘突出症行椎间盘切除术是一种有效的手术治疗方法。存在多种手术技术,包括OD、MD和MED。2007年的一项Cochrane综述确定OD是改善症状的有效治疗方法,并发现了MD的充分证据。然而,MED的证据不足。
对Medline和Embase进行系统评价。旨在识别2007年以后进行的比较OD与MD及MED且将Oswestry功能障碍指数(ODI)作为结局指标报告出来的随机对照试验。
共识别出4项随机对照试验。没有一项研究发现在任何时间点研究组之间的ODI评分存在显著差异。3项研究比较了MED与OD,1项研究比较了OD、MD和MED。规模最大的研究报告称MED组严重并发症数量增加。
有一些证据表明,在三级转诊中心由熟练掌握该技术的外科医生进行的MED与OD一样有效。