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研究儿童结肠运动功能的新技术。

Novel techniques to study colonic motor function in children.

作者信息

Belkind-Gerson Jaime, Tran Khoa, Di Lorenzo Carlo

机构信息

Pediatric Gastroenterology, Massachusetts General Hospital for Children, Boston, MA, USA.

出版信息

Curr Gastroenterol Rep. 2013 Aug;15(8):335. doi: 10.1007/s11894-013-0335-3.

DOI:10.1007/s11894-013-0335-3
PMID:23852568
Abstract

Colonic motility is an essential component of normal colonic physiology and it controls essential bodily functions such as stool propulsion, storage, and expulsion. Disordered colonic motility may present with constipation or diarrhea as well as associated symptoms such as bloating, gas, pain, incontinence, and others. In order to assess colonic motor function, practitioners may use studies that either investigate transit time or that evaluate peristaltic activity. Transit time is the result of both the effectiveness of propulsive pressures and the physical characteristics of the stools. Its measurement allows one to quantify the extent and severity of the colonic dysfunction and permits the assessment of response to therapy. Various methods exist to investigate colon transit time and motility. In this review, we will focus on newer techniques for these investigations, including: scintigraphic transit studies, anorectal manometry, colonic manometry, and studies using a wireless motility capsule.

摘要

结肠动力是正常结肠生理的重要组成部分,它控制着诸如粪便推进、储存和排出等基本身体功能。结肠动力紊乱可能表现为便秘或腹泻以及相关症状,如腹胀、气体、疼痛、失禁等。为了评估结肠运动功能,医生可以使用研究来调查传输时间或评估蠕动活动。传输时间是推进压力有效性和粪便物理特征的结果。其测量可以量化结肠功能障碍的程度和严重程度,并允许评估对治疗的反应。存在多种方法来研究结肠传输时间和动力。在本综述中,我们将重点关注这些研究的新技术,包括:闪烁扫描传输研究、肛门直肠测压、结肠测压以及使用无线动力胶囊的研究。

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本文引用的文献

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High-resolution colonic manometry accurately predicts colonic neuromuscular pathological phenotype in pediatric slow transit constipation.高分辨率结肠测压术可准确预测小儿慢传输型便秘的结肠神经肌肉病理表型。
Neurogastroenterol Motil. 2013 Jan;25(1):70-8.e8-9. doi: 10.1111/nmo.12016. Epub 2012 Oct 3.
2
Normal values for high-resolution anorectal manometry in healthy women: effects of age and significance of rectoanal gradient.健康女性高分辨率肛门直肠测压的正常值:年龄的影响和直肠肛门梯度的意义。
Am J Gastroenterol. 2012 Oct;107(10):1530-6. doi: 10.1038/ajg.2012.221. Epub 2012 Sep 18.
3
How common is colonic elongation in children with slow-transit constipation or anorectal retention?
随机试验:薄荷油(薄荷醇)在儿童中的药代动力学及对功能性腹痛儿童肠道动力的影响。
Br J Clin Pharmacol. 2022 Mar;88(3):1321-1333. doi: 10.1111/bcp.15076. Epub 2021 Oct 19.
4
Barriers in Neurogastroenterology and Motility Training Experience for Pediatric Gastroenterology Fellows.儿科胃肠病学研究员在神经胃肠病学和动力训练方面的障碍。
J Pediatr Gastroenterol Nutr. 2019 Jun;68(6):806-810. doi: 10.1097/MPG.0000000000002282.
5
Dietary exclusion of fructose and lactose after positive breath tests improved rapid-transit constipation in children.呼气试验呈阳性后,在饮食中排除果糖和乳糖可改善儿童的快速转运型便秘。
JGH Open. 2018 Aug 14;2(6):262-269. doi: 10.1002/jgh3.12079. eCollection 2018 Dec.
6
A double blind, placebo-controlled, randomized clinical trial that breast milk derived- BNR17 mitigated diarrhea-dominant irritable bowel syndrome.一项双盲、安慰剂对照、随机临床试验表明,母乳来源的BNR17可缓解以腹泻为主的肠易激综合征。
J Clin Biochem Nutr. 2018 Mar;62(2):179-186. doi: 10.3164/jcbn.17-73. Epub 2018 Jan 11.
7
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J Neurogastroenterol Motil. 2016 Jul 30;22(3):483-9. doi: 10.5056/jnm15128.
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Neurogastroenterol Motil. 2010 Dec;22(12):e340-9. doi: 10.1111/j.1365-2982.2010.01597.x.