Treviño R P, Pham T H, Edelstein S L
Social and Health Research Center, San Antonio, TX 78210, USA.
J Obes. 2013;2013:206074. doi: 10.1155/2013/206074. Epub 2013 Jun 19.
To date, studies examining the relation between body mass index percentile (BMI%) categories and health-related quality of life (QOL) measurements have not reported preference-weighted scores among ethnically diverse children. We report the associations between BMI% categories and preference-weighted scores among a large cohort of ethnically diverse sixth grade children who participated in the HEALTHY school-based type 2 diabetes risk factor prevention study. Health Utility Index 2 (HUI2) and Health Utility Index 3 (HUI3) and the feeling thermometer (FT) were the preference-weighted QOL instruments used to measure student's preference scores. Of 6358 consented students, 4979 (78.3%) had complete QOL, height, weight, and covariate data. Mean (SD) preference scores were 0.846 (0.160), 0.796 (0.237), and 0.806 (0.161) for the HUI2, HUI3, and FT, respectively. After adjusting for age, sex, blood glucose and insulin, Tanner stage, race/ethnicity, family history of diabetes, and educational attainment, children with severe obesity (>99%) had significantly lower preference scores compared to normal weight on all three instruments (HUI2 P = 0.013; HUI3 P = 0.025; and FT P < 0.001). Obese and severe obese categories were significantly associated with lower HUI2 functional ratings in the mobility domain and with lower HUI3 functional ratings in the speech domain.
迄今为止，研究身体质量指数百分位数（BMI%）类别与健康相关生活质量（QOL）测量之间关系的研究，尚未报告不同种族儿童的偏好加权分数。我们报告了参与“健康”校内2型糖尿病危险因素预防研究的一大群不同种族六年级儿童中，BMI%类别与偏好加权分数之间的关联。健康效用指数2（HUI2）、健康效用指数3（HUI3）和感觉温度计（FT）是用于测量学生偏好分数的偏好加权QOL工具。在6358名同意参与的学生中，4979名（78.3%）有完整的QOL、身高、体重和协变量数据。HUI2、HUI3和FT的平均（标准差）偏好分数分别为0.846（0.160）、0.796（0.237）和0.806（0.161）。在调整年龄、性别、血糖和胰岛素、坦纳分期、种族/民族、糖尿病家族史和教育程度后，与正常体重儿童相比，严重肥胖（>99%）儿童在所有三种工具上的偏好分数均显著较低（HUI2 P = 0.013；HUI3 P = 0.025；FT P < 0.001）。肥胖和严重肥胖类别与HUI2在活动领域的较低功能评分以及HUI3在言语领域的较低功能评分显著相关。
