Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška 4, 1000 Ljubljana, Slovenia.
Virus Res. 2013 Oct;177(1):113-7. doi: 10.1016/j.virusres.2013.07.011. Epub 2013 Jul 23.
Seewis virus, the shrew-borne hantavirus from Sorex araneus, has been molecularly detected in reservoir hosts in many different central European countries and Russia. Slovenia is a known endemic country for rodent-borne hantaviruses, therefore the aim of the study was to investigate the presence of shrew-borne hantaviruses in insectivores. Viral L, S and M segment have been recovered only from tissue samples of 7 S. araneus, despite several shrew species were tested. Phylogenetic analysis showed high genetic diversity of SWSV in Slovenia, ranging from 3 to 19.4% for different viral segments. The most divergent were M segment sequences, with 19.4% nucleotide divergence among Slovenian strains. Above that, different SWSV strains from Slovenia do not group into separate geographic clusters. While three separate genetic clades were determined, two of them were simultaneously present in one location at the same time.
在许多不同的中欧国家和俄罗斯，已经从鼩鼱属的鼩鼱中检测到了西维森病毒，这种由鼩鼱传播的汉坦病毒。斯洛文尼亚是已知的啮齿动物传播汉坦病毒的流行地区，因此本研究的目的是调查在食虫动物中是否存在由鼩鼱传播的汉坦病毒。尽管对几种鼩鼱进行了检测，但仅从 7 只鼩鼱属的组织样本中回收了病毒的 L、S 和 M 片段。系统进化分析显示，斯洛文尼亚的 SWSV 具有很高的遗传多样性，不同病毒片段的差异为 3%至 19.4%。最具差异的是 M 片段序列，斯洛文尼亚毒株之间的核苷酸差异为 19.4%。此外，来自斯洛文尼亚的不同 SWSV 株并未分为单独的地理群。虽然确定了三个单独的遗传分支，但其中两个同时存在于同一地点。
