Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, 651 Ilalo Street, Honolulu, HI 96813, USA.
Virol J. 2009 Nov 24;6:208. doi: 10.1186/1743-422X-6-208.
Recent identification of a newfound hantavirus, designated Seewis virus (SWSV), in the Eurasian common shrew (Sorex araneus), captured in Switzerland, corroborates decades-old reports of hantaviral antigens in this shrew species from Russia. To ascertain the spatial or geographic variation of SWSV, archival liver tissues from 88 Eurasian common shrews, trapped in Finland in 1982 and in Hungary during 1997, 1999 and 2000, were analyzed for hantavirus RNAs by reverse transcription-polymerase chain reaction. SWSV RNAs were detected in 12 of 22 (54.5%) and 13 of 66 (19.7%) Eurasian common shrews from Finland and Hungary, respectively. Phylogenetic analyses of S- and L-segment sequences of SWSV strains, using maximum likelihood and Bayesian methods, revealed geographic-specific genetic variation, similar to the phylogeography of rodent-borne hantaviruses, suggesting long-standing hantavirus-host co-evolutionary adaptation.
最近在瑞士捕获的欧亚普通鼩（Sorex araneus）中发现了一种新的汉坦病毒，命名为塞维斯病毒（SWSV），这证实了俄罗斯几十年来关于这种鼩鼱携带汉坦病毒抗原的报告。为了确定 SWSV 的空间或地理变异情况，对 1982 年在芬兰和 1997 年、1999 年和 2000 年在匈牙利捕获的 88 只欧亚普通鼩的肝脏组织进行了逆转录-聚合酶链反应分析，以检测汉坦病毒 RNA。在芬兰和匈牙利的 22 只和 66 只欧亚普通鼩中，分别有 12 只（54.5%）和 13 只（19.7%）检测到 SWSV RNA。使用最大似然法和贝叶斯法对 SWSV 株的 S-和 L-段序列进行系统发育分析，结果显示存在地理特异性遗传变异，类似于啮齿动物携带的汉坦病毒的系统地理学，表明长期以来汉坦病毒与宿主的共同进化适应。
