• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

荧光诊断在临床实践中的作用。

The role of fluorescence diagnosis in clinical practice.

机构信息

Clinical Department of Internal Diseases, Angiology and Physical Medicine, Center for Laser Diagnostics and Therapy, Silesian Medical University, Bytom.

出版信息

Onco Targets Ther. 2013 Jul 24;6:977-82. doi: 10.2147/OTT.S42074. Print 2013.

DOI:10.2147/OTT.S42074
PMID:23935372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3735341/
Abstract

Fluorescence diagnosis is a fast, easy, noninvasive, selective, and sensitive diagnostic tool for estimation of treatment results in oncology. In clinical practice the use of photodynamic diagnosis is focused on five targets: detection for prevention of malignant transformation precancerous changes, detection of neoplasmatic tissue in the early stages for fast removal, prevention of expansion and detection of recurrence of the cancer, monitoring therapy, and the possibility of excluding neoplasmatic disease. In this article, selected applications of fluorescence diagnosis at the Center for Laser Diagnostics and Therapy in Bytom, Poland, for each of these targets are presented.

摘要

荧光诊断是一种快速、简便、无创、具有选择性和高灵敏度的诊断工具,可用于评估肿瘤治疗效果。在临床实践中,光动力诊断的应用主要集中在五个目标上:预防恶性转化和癌前病变的检测,早期发现肿瘤组织以便快速切除,防止肿瘤的扩散和复发的检测,监测治疗效果,以及排除肿瘤性疾病的可能性。本文介绍了波兰比托姆激光诊断与治疗中心在这些目标中的每一个目标上,对荧光诊断的选择应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/a18e0c6bca2e/ott-6-977Fig20.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/44e0b66d7eec/ott-6-977Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/d831a90d7ac8/ott-6-977Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/766a2f24da7d/ott-6-977Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/19d1ebe279c6/ott-6-977Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/19ecc63e703c/ott-6-977Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/64f2dbf7a90e/ott-6-977Fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/4c9a89ff4e3e/ott-6-977Fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/6d7fed23f9fb/ott-6-977Fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/3ac61c0e1441/ott-6-977Fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/84fe6e6a15b8/ott-6-977Fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/c79d0f70bb7f/ott-6-977Fig11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/fa79b43aa435/ott-6-977Fig12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/d061d738e20c/ott-6-977Fig13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/eb14d23794cf/ott-6-977Fig14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/aff0f13ae359/ott-6-977Fig15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/c00132a7f8f8/ott-6-977Fig16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/3597be805d51/ott-6-977Fig17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/62dab2ce25f0/ott-6-977Fig18.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/fcc89fa4bbff/ott-6-977Fig19.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/a18e0c6bca2e/ott-6-977Fig20.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/44e0b66d7eec/ott-6-977Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/d831a90d7ac8/ott-6-977Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/766a2f24da7d/ott-6-977Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/19d1ebe279c6/ott-6-977Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/19ecc63e703c/ott-6-977Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/64f2dbf7a90e/ott-6-977Fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/4c9a89ff4e3e/ott-6-977Fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/6d7fed23f9fb/ott-6-977Fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/3ac61c0e1441/ott-6-977Fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/84fe6e6a15b8/ott-6-977Fig10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/c79d0f70bb7f/ott-6-977Fig11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/fa79b43aa435/ott-6-977Fig12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/d061d738e20c/ott-6-977Fig13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/eb14d23794cf/ott-6-977Fig14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/aff0f13ae359/ott-6-977Fig15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/c00132a7f8f8/ott-6-977Fig16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/3597be805d51/ott-6-977Fig17.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/62dab2ce25f0/ott-6-977Fig18.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/fcc89fa4bbff/ott-6-977Fig19.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/3735341/a18e0c6bca2e/ott-6-977Fig20.jpg

相似文献

1
The role of fluorescence diagnosis in clinical practice.荧光诊断在临床实践中的作用。
Onco Targets Ther. 2013 Jul 24;6:977-82. doi: 10.2147/OTT.S42074. Print 2013.
2
Clinical Trials and Basic Research in Photodynamic Diagnostics and Therapies from the Center for Laser Diagnostics and Therapy in Poland.波兰激光诊断与治疗中心的光动力诊断和治疗的临床研究与基础研究。
Photochem Photobiol. 2020 May;96(3):539-549. doi: 10.1111/php.13243. Epub 2020 Apr 29.
3
Autofluorescence endoscopy with "real-time" digital image processing in differential diagnostics of selected benign and malignant lesions in the oesophagus.应用“实时”数字图像处理的自体荧光内镜在食管中选择的良性和恶性病变的鉴别诊断中的应用。
Photodiagnosis Photodyn Ther. 2012 Mar;9(1):5-10. doi: 10.1016/j.pdpdt.2011.11.005. Epub 2011 Dec 23.
4
The role of autofluorescence diagnostics in the oral mucosa diseases.自体荧光诊断在口腔黏膜疾病中的作用。
Photodiagnosis Photodyn Ther. 2008 Sep;5(3):182-6. doi: 10.1016/j.pdpdt.2008.09.002. Epub 2008 Oct 31.
5
Methods for bladder cancer diagnosis - The role of autofluorescence and photodynamic diagnosis.膀胱癌诊断方法 - 自体荧光和光动力诊断的作用。
Photodiagnosis Photodyn Ther. 2019 Sep;27:141-148. doi: 10.1016/j.pdpdt.2019.05.036. Epub 2019 May 29.
6
Autofluorescence and Photofrin-induced fluorescence imaging and spectroscopy in an animal model of oral cancer.口腔癌动物模型中的自体荧光和血卟啉衍生物诱导荧光成像和光谱学。
Photodiagnosis Photodyn Ther. 2006 Sep;3(3):168-76. doi: 10.1016/j.pdpdt.2006.04.003. Epub 2006 Jun 9.
7
Usefulness of the computed tomography and magnetic resonance in evaluation of progress of treatment of the neoplasmatic diseases in children.计算机断层扫描和磁共振成像在评估儿童肿瘤性疾病治疗进展中的作用。
Pol J Radiol. 2012 Jul;77(3):46-52. doi: 10.12659/pjr.883374.
8
In vivo photo-detection of chemically induced premalignant lesions and squamous cell carcinoma of the rat palatal mucosa.大鼠腭黏膜化学诱导的癌前病变和鳞状细胞癌的体内光检测
J Photochem Photobiol B. 1997 Jun;39(2):156-66. doi: 10.1016/s1011-1344(96)00011-5.
9
[Clinical fluorescent diagnosis of tumors using photosensitizer photogem].[使用光敏剂光宝石进行肿瘤的临床荧光诊断]
Khirurgiia (Mosk). 1995(5):37-41.
10
New optical imaging technologies for bladder cancer: considerations and perspectives.膀胱癌新型光学成像技术:思考与展望。
J Urol. 2012 Aug;188(2):361-8. doi: 10.1016/j.juro.2012.03.127. Epub 2012 Jun 13.

引用本文的文献

1
Correlation of Preclinical Imaging Modalities and Immunohistochemistry for Tumor Hypoxia and Vasculature.临床前成像模式与肿瘤缺氧及血管系统免疫组织化学的相关性
In Vivo. 2025 Jan-Feb;39(1):55-79. doi: 10.21873/invivo.13804.
2
Fluorescence in neurosurgery: its therapeutic and diagnostic significance - a comprehensive review.神经外科中的荧光:其治疗与诊断意义——一篇综述
Ann Med Surg (Lond). 2024 May 23;86(7):4255-4261. doi: 10.1097/MS9.0000000000002218. eCollection 2024 Jul.
3
Multiplexed near infrared fluorescence lifetime imaging in turbid media.

本文引用的文献

1
Therapeutic effects of 5-ALA-induced photodynamic therapy in vulvar lichen sclerosus.5-ALA 诱导光动力疗法治疗外阴硬化性苔藓的疗效。
Photodiagnosis Photodyn Ther. 2005 Jun;2(2):157-60. doi: 10.1016/S1572-1000(05)00062-1. Epub 2005 Aug 3.
2
Fluorescent diagnosis of urinary bladder cancer-a comparison of two diagnostic modalities.荧光诊断膀胱癌——两种诊断方式的比较。
Photodiagnosis Photodyn Ther. 2004 May;1(1):23-6. doi: 10.1016/S1572-1000(04)00006-7.
3
Photodiagnosis and fluorescence imaging in clinical practice.临床实践中的光诊断和荧光成像。
多色近红外荧光寿命成像在混浊介质中。
J Biomed Opt. 2024 Feb;29(2):026004. doi: 10.1117/1.JBO.29.2.026004. Epub 2024 Feb 29.
4
Nanoscatterer-Assisted Fluorescence Amplification Technique.纳米散射体辅助荧光放大技术
Nanomaterials (Basel). 2023 Oct 30;13(21):2875. doi: 10.3390/nano13212875.
5
Application of near-infrared fluorescence imaging in theranostics of gastrointestinal tumors.近红外荧光成像在胃肠道肿瘤诊疗中的应用。
Gastroenterol Rep (Oxf). 2023 Sep 27;11:goad055. doi: 10.1093/gastro/goad055. eCollection 2023.
6
Pulmonary Sarcoidosis: Experimental Models and Perspectives of Molecular Diagnostics Using Quantum Dots.肺结节病:量子点用于分子诊断的实验模型和前景。
Int J Mol Sci. 2023 Jul 10;24(14):11267. doi: 10.3390/ijms241411267.
7
Native fluorescence of tear fluid as a tool for diagnostics of glaucoma.泪液的固有荧光作为青光眼诊断的一种工具。
RSC Adv. 2021 Mar 15;11(18):10842-10846. doi: 10.1039/d1ra00473e. eCollection 2021 Mar 10.
8
Velscope guided oral cancer screening: A ray of hope in early oral cancer diagnosis.VELscope 引导下的口腔癌筛查:早期口腔癌诊断中的一线希望。
J Oral Maxillofac Pathol. 2021 Sep-Dec;25(3):548-549. doi: 10.4103/jomfp.JOMFP_315_20. Epub 2022 Jan 11.
9
Advances in Management of Bladder Cancer-The Role of Photodynamic Therapy.膀胱癌治疗进展——光动力疗法的作用。
Molecules. 2022 Jan 23;27(3):731. doi: 10.3390/molecules27030731.
10
Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment.采用药物、纳米颗粒和肿瘤微环境的多尺度成像研究纳米医学的空间异质性。
Theranostics. 2020 Jan 1;10(4):1884-1909. doi: 10.7150/thno.38625. eCollection 2020.
Photodiagnosis Photodyn Ther. 2004 May;1(1):9-12. doi: 10.1016/S1572-1000(04)00004-3.
4
Autofluorescence endoscopy with "real-time" digital image processing in differential diagnostics of selected benign and malignant lesions in the oesophagus.应用“实时”数字图像处理的自体荧光内镜在食管中选择的良性和恶性病变的鉴别诊断中的应用。
Photodiagnosis Photodyn Ther. 2012 Mar;9(1):5-10. doi: 10.1016/j.pdpdt.2011.11.005. Epub 2011 Dec 23.
5
Autofluorescence imaging endoscopy for identification and assessment of inflammatory ulcerative colitis.自体荧光成像内镜用于识别和评估炎症性溃疡性结肠炎。
World J Gastroenterol. 2011 Dec 14;17(46):5110-6. doi: 10.3748/wjg.v17.i46.5110.
6
Autofluorescence imaging and magnification endoscopy.自发荧光成像和放大内镜检查。
World J Gastroenterol. 2011 Jan 7;17(1):9-14. doi: 10.3748/wjg.v17.i1.9.
7
The future of endoscopy.内窥镜检查的未来。
J Gastroenterol Hepatol. 2010 Jun;25(6):1051-7. doi: 10.1111/j.1440-1746.2010.06333.x.
8
Twenty years of experience with PDD and PDT in Poland--review.波兰二十年的光动力诊断和光动力治疗经验——综述
Photodiagnosis Photodyn Ther. 2009 Jun;6(2):73-8. doi: 10.1016/j.pdpdt.2009.07.003. Epub 2009 Aug 8.
9
Optical biopsy using spectral camera in BCC and oral leukoplakia.使用光谱相机对基底细胞癌和口腔白斑进行光学活检。
Photodiagnosis Photodyn Ther. 2008 Dec;5(4):271-5. doi: 10.1016/j.pdpdt.2008.10.001. Epub 2008 Nov 8.
10
Photodiagnosis for cutaneous malignancy: a brief clinical and technical review.皮肤恶性肿瘤的光诊断:简要的临床与技术综述
Photodiagnosis Photodyn Ther. 2008 Dec;5(4):247-50. doi: 10.1016/j.pdpdt.2009.01.002.