Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore.
Chem Soc Rev. 2013 Dec 7;42(23):9055-70. doi: 10.1039/c3cs60169b. Epub 2013 Aug 27.
Imidazolium salts, distinct from their parent imidazoles, are made up of a discrete cation and anion pair, and have found widespread utility as ionic liquids. A lesser known function of such imidazolium salts includes the application of these salts in biological systems, and several areas of bio-applications, including antitumour, antimicrobial, antioxidant and bioengineering applications, will be presented and discussed in this review. The wide-ranging applications and versatility of these imidazolium salts stem from the ease of their structural variation, in which properties such as amphiphilicity, lipophilicity and solubility can be tuned.
咪唑鎓盐与母体咪唑不同，由离散的阳离子和阴离子对组成，已被广泛用作离子液体。此类咪唑鎓盐鲜为人知的功能之一是将这些盐应用于生物系统，本综述将介绍和讨论它们在包括抗肿瘤、抗菌、抗氧化和生物工程应用等几个生物应用领域的应用。这些咪唑鎓盐的广泛应用和多功能性源于其结构变化的容易程度，通过这种变化可以调整亲脂性、疏水性和溶解度等性质。
