Meng Jiajia, Wang Xiaohan, Xu Dan, Fu Xiaoxiang, Zhang Xuping, Lai Daowan, Zhou Ligang, Zhang Guozhen
Key Laboratory of Plant Pathology, Ministry of Agriculture/Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Molecules. 2016 Jun 1;21(6):715. doi: 10.3390/molecules21060715.
Sorbicillinoids are important hexaketide metabolites derived from fungi. They have a variety of biological activities including cytotoxic, antioxidant, antiviral and antimicrobial activity. The unique structural features of the sorbicillinoids make them attractive candidates for developing new pharmaceutical and agrochemical agents. About 90 sorbicillinoids have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, structures, and biological activities.
柄曲霉素类化合物是源自真菌的重要六酮类代谢产物。它们具有多种生物活性,包括细胞毒性、抗氧化、抗病毒和抗菌活性。柄曲霉素类化合物独特的结构特征使其成为开发新型药物和农用化学品的有吸引力的候选物。在过去几十年中已报道了约90种柄曲霉素类化合物。本综述旨在简要总结它们的存在、结构和生物活性。