Department of Food and Nutrition, Pukyung National University, Busan 608-737, Korea.
Nutr Res Pract. 2013 Oct;7(5):400-8. doi: 10.4162/nrp.2013.7.5.400. Epub 2013 Oct 1.
Obesity may be the consequence of various environmental or genetic factors, which may be highly correlated with each other. We aimed to examine whether grandmaternal and maternal obesity and environmental risk factors are related to obesity in daughters. Daughters (n = 182) recruited from female students, their mothers (n = 147) and their grandmothers (n = 67) were included in this study. Multivariable logistic regression was used to analyze the association between the daughter's obesity and maternal, grandmaternal, and environmental factors. Maternal heights of 161-175cm (OD: 8.48, 95% CI: 3.61-19.93) and 156-160 cm (2.37, 1.14-4.91) showed positive associations with a higher height of daughter, compared to those of 149-155 cm. Mothers receiving a university or a higher education had a significant OR (3.82, 1.27-11.50) for a higher height of daughter compared to those having a low education (elementary school). Mother having the heaviest weight at current time (59-80 kg, 3.78, 1.73-8.28) and the heaviest weight at 20 years of age (51-65 kg, 3.17, 1.53-6.55) had significant associations with a higher height of daughters, compared to those having the lightest weight at the same times. There was no association between the height, weight, and BMI of daughters and the characteristics and education of her grandmothers. In conclusion, although genetic factors appear to influence the daughter's height more than environmental factors, the daughter's weight appears to be more strongly associated with individual factors than the genetic factors.
肥胖可能是多种环境或遗传因素的结果,这些因素可能高度相关。我们旨在研究祖母和母亲肥胖以及环境危险因素是否与女儿肥胖有关。这项研究纳入了从女学生、她们的母亲(n=147)和祖母(n=67)中招募的女儿(n=182)。多变量逻辑回归用于分析女儿肥胖与母亲、祖母和环境因素之间的关系。与 149-155cm 身高的母亲相比,身高为 161-175cm(优势比[OR]:8.48,95%置信区间[CI]:3.61-19.93)和 156-160cm(OR:2.37,1.14-4.91)的母亲与女儿较高的身高呈正相关。与接受过小学及以下教育的母亲相比,接受过大学或更高教育的母亲的女儿身高较高的可能性显著增加(OR:3.82,1.27-11.50)。与体重最轻的母亲相比,目前体重为 59-80kg(OR:3.78,1.73-8.28)和 20 岁时体重为 51-65kg(OR:3.17,1.53-6.55)的母亲,其女儿身高较高的可能性显著增加。女儿的身高、体重和体重指数与她祖母的特征和教育水平之间没有关联。结论:尽管遗传因素似乎对女儿的身高影响大于环境因素,但女儿的体重似乎与个体因素的关联比遗传因素更密切。