The College of New Jersey , Ewing, NJ, USA.
J Sports Sci Med. 2006 Jun 1;5(2):182-93. eCollection 2006.
For the past 50 years anabolic steroids have been at the forefront of the controversy surrounding performance enhancing drugs. For almost half of this time no attempt was made by sports governing bodies to control its use, and only recently have all of the major sports governing bodies in North America agreed to ban from competition and punish athletes who test positive for anabolic steroids. These punitive measures were developed with the primary concern for promotion of fair play and eliminating potential health risks associated with androgenic-anabolic steroids. Yet, controversy exists whether these testing programs deter anabolic steroid use. Although the scope of this paper does not focus on the effectiveness of testing, or the issue of fair play, it is of interest to understand why many athletes underestimate the health risks associated from these drugs. What creates further curiosity is the seemingly well-publicized health hazards that the medical community has depicted concerning anabolic steroidabuse. Is there something that the athletes know, or are they simply naïve regarding the dangers? The focus of this review is to provide a brief history of anabolic steroid use in North America, the prevalence of its use in both athletic and recreational populations and its efficacy. Primary discussion will focus on health issues associated with anabolic steroid use with an examination of the contrasting views held between the medical community and the athletes that are using these ergogenic drugs. Existing data suggest that in certain circumstances the medical risk associated with anabolic steroid use may have been somewhat exaggerated, possibly to dissuade use in athletes. Key PointsFor many years the scientific and medical communities depicted a lack of efficacy and serious adverse effects from anabolic steroid use.Clinical case studies continue to link anabolic steroid administration with myocardial infarct, suicide, and cancer, evidence to support a cause and effect relationship is lacking.It may be other contributing factors (i.e. genetic predisposition, diet, etc.) that play a substantial role and potentiate the harmful effects from anabolic steroids.
在过去的 50 年中,合成代谢类固醇一直是围绕着提高运动表现的药物的争议的前沿。在这段时间的近一半时间里,体育管理机构没有试图控制其使用,直到最近,北美所有主要的体育管理机构才同意禁止运动员使用并惩罚那些检测出使用合成代谢类固醇呈阳性的运动员。这些惩罚性措施的制定主要是为了促进公平竞争和消除与雄激素-合成代谢类固醇相关的潜在健康风险。然而,关于这些测试计划是否能阻止合成代谢类固醇的使用仍存在争议。尽管本文的范围不集中在测试的有效性或公平竞争的问题上,但了解为什么许多运动员低估这些药物相关的健康风险是很有意义的。更令人好奇的是,医学界描绘的与滥用合成代谢类固醇有关的健康危害似乎广为人知。运动员们是否知道一些事情,还是他们对这些危险一无所知?本文回顾的重点是提供北美的合成代谢类固醇使用的简要历史,其在竞技和娱乐人群中的使用普遍性及其功效。主要讨论将集中在与合成代谢类固醇使用相关的健康问题上,并检查医学界和使用这些增强能量药物的运动员之间的观点对比。现有数据表明,在某些情况下,与合成代谢类固醇使用相关的医疗风险可能被有些夸大了,这可能是为了劝阻运动员使用。
多年来,科学界和医学界都描绘了合成代谢类固醇使用缺乏疗效和严重不良反应的情况。
临床病例研究继续将合成代谢类固醇的使用与心肌梗死、自杀和癌症联系起来,但缺乏支持因果关系的证据。
可能是其他因素(如遗传易感性、饮食等)发挥了重要作用,并加剧了合成代谢类固醇的有害影响。