Alhumaidi Mohammed, Agha Adnan, Dewish Mohamed
King Khalid University, Department of Medicine, Abha, Saudi Arabia.
Blackpool Victoria Hospital, SPR Endocrinology & Diabetes, Blackpool, UK.
Maedica (Bucur). 2013 Sep;8(3):231-6.
Type-2 diabetes mellitus and Vitamin D deficiency are both common in Saudi Arabian population. New roles of vitamin D have emerged recently especially in the prevention of cardiovascular disease, cancer and insulin resistance.
To estimate 25-OH vitamin D deficiency in patients with type-2 diabetes mellitus in comparison to normal age-matched non-diabetic control population.
A Randomized Case-Control study was done in three tertiary care hospitals in Southern Region, Saudi Arabia from June 2010 to June 2012 and 345 patients were selected; 172 in the diabetic group and 173 in the non-diabetic group. Biochemical workup and 25-OH vitamin D levels were done.
The mean serum 25-OH vitamin D levels in the diabetic group were 15.7 + 7.5 ng/mL as compared healthy non-diabetic group having 11.1 + 5.9 ng/mL and a total of 340 patients (98.5%) from both groups were found to be deficient in 25-OH vitamin D which is the highest reported so far in Saudi Arabia.
The population in our study was generally deficient in 25-OH vitamin D irrespective of diabetes mellitus indicating a greater need for vitamin D supplementation.
2型糖尿病和维生素D缺乏在沙特阿拉伯人群中都很常见。维生素D最近出现了新的作用，特别是在预防心血管疾病、癌症和胰岛素抵抗方面。
与年龄匹配的正常非糖尿病对照人群相比，评估2型糖尿病患者中25-羟基维生素D缺乏情况。
2010年6月至2012年6月在沙特阿拉伯南部地区的三家三级护理医院进行了一项随机病例对照研究，共选取345例患者；糖尿病组172例，非糖尿病组173例。进行了生化检查和25-羟基维生素D水平检测。
糖尿病组血清25-羟基维生素D平均水平为15.7±7.5纳克/毫升，健康非糖尿病组为11.1±5.9纳克/毫升，两组共有340例患者（98.5%）被发现25-羟基维生素D缺乏，这是沙特阿拉伯迄今为止报道的最高比例。
我们研究中的人群普遍存在25-羟基维生素D缺乏，无论是否患有糖尿病，这表明更需要补充维生素D。
