Guzman-Holst Adriana, Petrozzi Veronica, Velez Claudia, Gupta Vinay, Ochoa Theresa J, Juliao Patricia
GSK, Building WN23, Avenue Fleming 20, 1300, Wavre, Belgium.
GSK, Lima, Peru.
Infect Dis Ther. 2023 Apr;12(4):1151-1173. doi: 10.1007/s40121-023-00788-z. Epub 2023 Mar 25.
For pregnant women, vaccination with inactivated influenza vaccine (IIV) and tetanus, diphtheria, acellular pertussis vaccine (Tdap) is recommended. In Peru, uptake is nonetheless low. A study was conducted to identify factors affecting maternal vaccination coverage. The study's primary objectives were to describe the knowledge, attitudes, and practices regarding maternal immunization among pregnant/postpartum women and health care professionals (HCPs). The secondary objective was to determine the vaccination coverage and the impact of Ministry of Health (MOH) recommendations.
An observational multicenter, cross-sectional survey study was conducted from February 1, 2021 to June 30, 2021 in five cities in Peru. Two surveys were conducted to assess knowledge, attitudes, and practices concerning maternal immunization: one among pregnant/postpartum women and one among HCPs.
Participants were 668 pregnant/postpartum women with a mean age of 29.6 years and 219 HCPs-mostly midwives (46.6%) and obstetricians/gynecologists (44.7%). Of the pregnant/postpartum women, 66.9% knew that, in general, vaccinations are given for prevention, and 98.5% believed vaccines are important. Nonetheless, 69.6% of pregnant/postpartum women had poor or moderate knowledge of maternal vaccination. Disease knowledge of influenza (89.1%) and tetanus (87.0%) was high, while knowledge of pertussis (37.7%) was low. Women agreed/strongly agreed that they would get vaccinated with Tdap if a doctor (96.3%), midwife (88.9%), or nurse (72.0%) recommended it. Of the HCPs, 81.3% routinely recommended Tdap vaccination for pregnant women.
To enhance vaccine acceptance in pregnant women in Peru, we must improve knowledge of the diseases, MOH recommendations, and benefits of the offered vaccinations. HCPs could provide this vaccination knowledge and information along with their vaccination recommendation as the pregnant/postpartum women indicated they would take the vaccines if recommended by their HCPs. Our findings are important for the successful implementation of maternal immunization programs in Peru.
对于孕妇,建议接种灭活流感疫苗(IIV)以及破伤风、白喉、无细胞百日咳疫苗(Tdap)。然而在秘鲁,这些疫苗的接种率很低。开展了一项研究以确定影响孕产妇疫苗接种覆盖率的因素。该研究的主要目标是描述孕妇/产后妇女及医护人员(HCP)对孕产妇免疫的知识、态度和行为。次要目标是确定疫苗接种覆盖率以及秘鲁卫生部(MOH)建议的影响。
于2021年2月1日至2021年6月30日在秘鲁的五个城市开展了一项观察性多中心横断面调查研究。进行了两项调查以评估有关孕产妇免疫的知识、态度和行为:一项针对孕妇/产后妇女,另一项针对医护人员。
参与者为668名孕妇/产后妇女,平均年龄29.6岁,以及219名医护人员,其中大多数是助产士(46.6%)和妇产科医生(44.7%)。在孕妇/产后妇女中,66.9%知道一般来说接种疫苗是用于预防,98.5%认为疫苗很重要。尽管如此,69.6%的孕妇/产后妇女对孕产妇疫苗接种的知识掌握得较差或一般。对流感(89.1%)和破伤风(87.0%)的疾病知识了解程度较高,而对百日咳(37.7%)的知识了解程度较低。如果医生(96.3%)、助产士(88.9%)或护士(72.0%)推荐,女性同意/非常同意她们会接种Tdap疫苗。在医护人员中,81.3%会定期为孕妇推荐接种Tdap疫苗。
为提高秘鲁孕妇对疫苗的接受度,我们必须增进对疾病、秘鲁卫生部建议以及所提供疫苗益处的了解。由于孕妇/产后妇女表示如果医护人员推荐她们就会接种疫苗,医护人员可以在推荐疫苗的同时提供这种疫苗接种知识和信息。我们的研究结果对于秘鲁成功实施孕产妇免疫计划很重要。