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植物化合物对人类肠道病毒的控制。

Phytocompounds for the control of human enteric viruses.

机构信息

Department of Food Science and Technology, University of Tennessee-Knoxville, 2600 River Drive, Room 102 FSPB, Knoxville, TN 37996, United States.

出版信息

Curr Opin Virol. 2014 Feb;4:44-9. doi: 10.1016/j.coviro.2013.12.006. Epub 2014 Jan 14.

Abstract

Plant extracts and associated polyphenols are known for their varied health benefits that include antioxidant effects and antimicrobial properties. The increasing consumer demand for cost-effective and natural alternatives to chemically-synthesized antimicrobials and therapeutics that are also sustainable makes the field of phytochemical research rather intriguing and challenging. Human enteric viruses are increasingly recognized worldwide as significant causes of human disease in adults and children, alike. In the absence of available vaccines for the human noroviruses, plant extracts are gaining popularity for the prevention and treatment of viral diseases. Research on plant extracts (particularly polyphenols derived from fruits) for human enteric virus control will be briefly summarized in this article.

摘要

植物提取物及其相关多酚因其多种健康益处而闻名,包括抗氧化作用和抗菌特性。消费者对具有成本效益和可持续性的化学合成抗菌剂和治疗剂的天然替代品的需求不断增加,这使得植物化学研究领域既有趣又具有挑战性。人类肠道病毒在世界范围内越来越被认为是成人和儿童疾病的重要原因。由于目前尚无针对人类诺如病毒的疫苗,植物提取物在预防和治疗病毒疾病方面越来越受欢迎。本文将简要总结植物提取物(特别是水果来源的多酚)在控制人类肠道病毒方面的研究。

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本文引用的文献

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Norovirus disease in the United States.美国诺如病毒病。
Emerg Infect Dis. 2013 Aug;19(8):1198-205. doi: 10.3201/eid1908.130465.
2
The pomegranate: effects on bacteria and viruses that influence human health.石榴:影响人类健康的细菌和病毒的作用。
Evid Based Complement Alternat Med. 2013;2013:606212. doi: 10.1155/2013/606212. Epub 2013 May 20.
3
Grape seed extract for foodborne virus reduction on produce.葡萄籽提取物用于减少农产品食源性病原体。
Food Microbiol. 2013 May;34(1):1-6. doi: 10.1016/j.fm.2012.10.006. Epub 2012 Nov 16.
5
Naturally occurring flavonoids against human norovirus surrogates.天然类黄酮抗人诺如病毒替代物。
Food Environ Virol. 2013 Jun;5(2):97-102. doi: 10.1007/s12560-013-9106-4. Epub 2013 Feb 15.

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