Bell Aleeca F, Erickson Elise N, Carter C Sue
J Midwifery Womens Health. 2014 Jan-Feb;59(1):35-42: quiz 108. doi: 10.1111/jmwh.12101. Epub 2014 Jan 28.
Emerging research raises questions that synthetic oxytocin during childbirth may alter the endogenous oxytocin system and influence maternal stress, mood, and behavior. Endogenous oxytocin is a key component in the transition to motherhood, affecting molecular pathways that buffer stress reactivity, support positive mood, and regulate healthy mothering behaviors (including lactation). Synthetic oxytocin is widely used throughout labor and postpartum care in modern birth. Yet research on the implications beyond labor of maternal exposure to perinatal synthetic oxytocin is rare. In this article, we review oxytocin-related biologic pathways and behaviors associated with the transition to motherhood and evidence supporting the need for further research on potential effects of intrapartum oxytocin beyond labor. We include a primer on oxytocin at the molecular level.
新出现的研究提出了一些问题，即分娩期间使用的合成催产素可能会改变内源性催产素系统，并影响母亲的压力、情绪和行为。内源性催产素是向母亲角色转变过程中的关键组成部分，它影响着缓冲应激反应性、支持积极情绪以及调节健康育儿行为（包括哺乳）的分子途径。合成催产素在现代分娩的整个产程和产后护理中被广泛使用。然而，关于围产期母亲接触合成催产素对分娩之外影响的研究却很少。在本文中，我们回顾了与向母亲角色转变相关的催产素相关生物学途径和行为，以及支持进一步研究产程中催产素对分娩之外潜在影响的必要性的证据。我们还包括了分子水平上催产素的入门知识。
