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创伤后应激障碍和情绪聚焦支持性治疗的 7 天强化和标准每周认知疗法的随机对照试验。

A randomized controlled trial of 7-day intensive and standard weekly cognitive therapy for PTSD and emotion-focused supportive therapy.

出版信息

Am J Psychiatry. 2014 Mar;171(3):294-304. doi: 10.1176/appi.ajp.2013.13040552.

Abstract

OBJECTIVE

Psychological treatments for posttraumatic stress disorder (PTSD) are usually delivered once or twice a week over several months. It is unclear whether they can be successfully delivered over a shorter period of time. This clinical trial had two goals: to investigate the acceptability and efficacy of a 7-day intensive version of cognitive therapy for PTSD and to investigate whether cognitive therapy has specific treatment effects by comparing intensive and standard weekly cognitive therapy with an equally credible alternative treatment.

METHOD

Patients with chronic PTSD (N=121) were randomly allocated to 7-day intensive cognitive therapy for PTSD, 3 months of standard weekly cognitive therapy, 3 months of weekly emotion-focused supportive therapy, or a 14-week waiting list condition. The primary outcomes were change in PTSD symptoms and diagnosis as measured by independent assessor ratings and self-report. The secondary outcomes were change in disability, anxiety, depression, and quality of life. Evaluations were conducted at the baseline assessment and at 6 and 14 weeks (the posttreatment/wait assessment). For groups receiving treatment, evaluations were also conducted at 3 weeks and follow-up assessments at 27 and 40 weeks after randomization. All analyses were intent-to-treat.

RESULTS

At the posttreatment/wait assessment, 73% of the intensive cognitive therapy group, 77% of the standard cognitive therapy group, 43% of the supportive therapy group, and 7% of the waiting list group had recovered from PTSD. All treatments were well tolerated and were superior to waiting list on nearly all outcome measures; no difference was observed between supportive therapy and waiting list on quality of life. For primary outcomes, disability, and general anxiety, intensive and standard cognitive therapy were superior to supportive therapy. Intensive cognitive therapy achieved faster symptom reduction and comparable overall outcomes to standard cognitive therapy.

CONCLUSIONS

Cognitive therapy for PTSD delivered intensively over little more than a week was as effective as cognitive therapy delivered over 3 months. Both had specific effects and were superior to supportive therapy. Intensive cognitive therapy for PTSD is a feasible and promising alternative to traditional weekly treatment.

摘要

目的

创伤后应激障碍(PTSD)的心理治疗通常是在几个月内每周进行一到两次。目前尚不清楚它们是否可以在更短的时间内成功进行。本临床试验有两个目标:一是研究 PTSD 7 天强化认知疗法的可接受性和疗效;二是通过比较强化认知疗法和标准每周认知疗法与同等可信的替代治疗,研究认知疗法是否具有特定的治疗效果。

方法

将 121 名慢性 PTSD 患者随机分配到 PTSD7 天强化认知疗法、3 个月标准每周认知疗法、3 个月每周情绪聚焦支持性疗法或 14 周候补组。主要结局是由独立评估者评分和自我报告测量的 PTSD 症状和诊断的变化。次要结局是残疾、焦虑、抑郁和生活质量的变化。评估在基线评估时以及治疗后 6 周和 14 周(等待治疗评估)进行。对于接受治疗的组,在 3 周和随机分组后 27 周和 40 周的随访评估时也进行了评估。所有分析均为意向治疗分析。

结果

在等待治疗/等待评估时,强化认知疗法组的 73%、标准认知疗法组的 77%、支持性疗法组的 43%和候补组的 7%从 PTSD 中康复。所有治疗均耐受良好,在几乎所有结果测量指标上均优于候补组;支持性疗法与候补组在生活质量上无差异。对于主要结局、残疾和一般焦虑,强化和标准认知疗法均优于支持性疗法。强化认知疗法实现了更快的症状缓解,总体结果与标准认知疗法相当。

结论

创伤后应激障碍的认知疗法在一周多一点的时间内强化治疗与 3 个月的治疗一样有效。两者都有特定的效果,并且优于支持性疗法。创伤后应激障碍的强化认知疗法是传统每周治疗的一种可行且有前途的替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a764/4082238/7cf1f3e14343/emss-57341-f0001.jpg

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