González Gilberto
Department of Endocrinology; School of Medicine; Pontificia Universidad Católica de Chile; Santiago, Chile.
Dermatoendocrinol. 2013 Jan 1;5(1):117-20. doi: 10.4161/derm.24807.
Vitamin D status has been extensively studied throughout the world. However, most of the studies are from North America, Europe and Oceania. This review describes published evidence on vitamin D status among healthy postmenopausal women in South America, where food is not fortified with vitamin D. A literature search identified ten studies from only three countries in the region: Argentina, Brazil and Chile. These studies reported a high prevalence of vitamin D deficiency, in spite of their location at latitudes with abundant sunlight throughout the year. In studies with proper design, a clear North-South gradient was revealed with higher 25(OH)D levels toward the equator. Seasonal changes in 25(OH)D were more likely to be detected in younger subjects. These results are very similar to what has been reported in the Northern Hemisphere and they emphasize the importance of recommendations for a higher vitamin D intake in this population from South America.
维生素D状况在全球范围内都得到了广泛研究。然而,大多数研究来自北美、欧洲和大洋洲。本综述描述了南美洲健康绝经后女性维生素D状况的已发表证据,该地区食物未添加维生素D。文献检索发现该地区仅有三个国家(阿根廷、巴西和智利)的十项研究。尽管这些国家地处全年阳光充足的纬度地区,但这些研究报告维生素D缺乏的患病率很高。在设计合理的研究中,呈现出明显的南北梯度,越靠近赤道25(OH)D水平越高。年轻受试者中更易检测到25(OH)D的季节性变化。这些结果与北半球所报告的非常相似,它们强调了对南美洲这一人群提高维生素D摄入量建议的重要性。