Kanthal Lakshmi Kanta, Dey Akalanka, Satyavathi K, Bhojaraju P
Department of Pharmacology, Koringa College of Pharmacy, Tallarevu Mandal, Andhra Pradesh, India.
Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India.
Pharmacognosy Res. 2014 Jan;6(1):58-61. doi: 10.4103/0974-8490.122919.
The presence of phytochemical constitutes has been reported from species of the Compositae (Asteraceae). Hitherto no reports exist on the phytochemical components and biological activity of Lactuca runcinata DC.
The present study was designed to determine the bioactive compounds in the whole plant methanol extract of Lactuca runcinata.
Phytochemical screening of the entire herb of Lactuca runcinata DC revealed the presence of some bio-active components. Gas chromatography-mass spectrometry (GC-MS) analysis of the whole plant methanol extract of Lactuca runcinata was performed on a GC-MS equipment (Thermo Scientific Co.) Thermo GC-TRACE ultra ver.: 5.0, Thermo MS DSQ II.
The phytochemical tests showed the presence of alkaloids, cardiac glycosides, flavonoids, phenols, phlobatannin, reducing sugars, saponins, steroids, tannins, terpenoids, volatile oils, carbohydrates, and protein/amino acids in methanolic extract of L. runcinata. The GC-MS analysis has shown the presence of different phytochemical compounds in the methanolic extract of Lactuca runcinata. A total of 21 compounds were identified representing 84.49% of total methanolic extract composition.
From the results, it is evident that Lactuca runcinata contains various phytocomponents and is recommended as a plant of phytopharmaceutical importance.
菊科（菊苣科）植物中已报道含有植物化学成分。迄今为止，尚未有关于野莴苣植物化学成分和生物活性的报道。
本研究旨在确定野莴苣全株甲醇提取物中的生物活性化合物。
对野莴苣全草进行植物化学筛选，发现了一些生物活性成分。使用气相色谱 - 质谱联用仪（赛默飞世尔科技公司，Thermo GC-TRACE ultra ver.: 5.0，Thermo MS DSQ II）对野莴苣全株甲醇提取物进行气相色谱 - 质谱（GC-MS）分析。
植物化学测试表明，野莴苣甲醇提取物中含有生物碱、强心苷、黄酮类、酚类、鞣红、还原糖、皂苷、甾体、单宁、萜类、挥发油、碳水化合物以及蛋白质/氨基酸。GC-MS分析表明，野莴苣甲醇提取物中存在不同的植物化学化合物。共鉴定出21种化合物，占甲醇提取物总成分的84.49%。
从结果来看，显然野莴苣含有多种植物成分，被推荐为具有植物药学重要性的植物。
