von Klitzing Kai, White Lars O, Otto Yvonne, Fuchs Sandra, Egger Helen L, Klein Annette M
Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University of Leipzig, Leipzig, Germany.
J Child Psychol Psychiatry. 2014 Oct;55(10):1107-16. doi: 10.1111/jcpp.12222. Epub 2014 Mar 14.
The threshold for clinical relevance of preschool anxiety has recently come under increasing scrutiny in view of large variations in prevalence estimates. We studied the impact of presence/absence of additional depressive comorbidity (symptoms and/or diagnosis) on preschoolers with anxiety disorders in relation to clinical phenomenology, family, and peer problems compared to healthy controls.
A population of 1738 preschoolers were screened and oversampled for internalizing symptoms from community sites, yielding a sample of 236 children.
Using a multi-informant approach (mother, father, teacher, child), we found evidence that children with anxiety disorders and depressive comorbidity display a greater internalizing symptom-load, more peer problems and live in families with more psychosocial impairment (poor family functioning, family adversity, maternal mental health problems). The pure anxiety group was merely dissociable from controls with regard to internalizing symptoms and family adversity.
The presence of depressive comorbidity in anxiety disorders may mark the transition to a more detrimental and impairing disorder at preschool age.
鉴于患病率估计存在很大差异,学龄前焦虑症临床相关性的阈值最近受到越来越多的审视。我们研究了与健康对照组相比,是否存在额外的抑郁共病(症状和/或诊断)对患有焦虑症的学龄前儿童在临床现象学、家庭和同伴问题方面的影响。
对1738名学龄前儿童进行筛查,并对社区场所的内化症状进行过度抽样,得到236名儿童的样本。
采用多信息提供者方法(母亲、父亲、教师、儿童),我们发现有证据表明,患有焦虑症和抑郁共病的儿童表现出更大的内化症状负担、更多的同伴问题,并且生活在心理社会损害更大(家庭功能差、家庭逆境、母亲心理健康问题)的家庭中。纯焦虑组在内化症状和家庭逆境方面仅与对照组有差异。
焦虑症中抑郁共病的存在可能标志着在学龄前向更有害和致残性疾病的转变。