偏头痛中的代谢综合征：一项病例对照研究。
Metabolic syndrome in migraine headache: A case-control study.
作者信息
Salmasi Mehrzad, Amini Laya, Javanmard Shaghayegh Haghjooy, Saadatnia Mohammad
机构信息
Isfahan Neurosciences Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
Physiology Research Center, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Res Med Sci. 2014 Jan;19(1):13-7.
BACKGROUND
The correlation of metabolic syndrome and migraine headache was evaluated in some previous studies. However there is no study that compared the prevalence of metabolic syndrome in the patients with and without migraine. Control of coincidental factors such as metabolic syndrome reduces therapeutic resistance in migrainous patients. The aim of this study was to compare prevalence of metabolic syndrome in patients with and without migraine headache.
MATERIALS AND METHODS
200 migrainous patients diagnosed according to International Headache Society and 200 healthy controls without migraine enrolled in this study. Metabolic syndrome was diagnosed according to ATP III criteria in these two groups and compared with each other.
RESULTS
In this study, 17% (34) of migrainous patients and 15% (30) of healthy control without migraine had metabolic syndrome. (P = 0.585). Of the metabolic syndrome components, body mass index (P = 0.05) and waist circumference in migrainous (P = 0.03) were significantly more frequent.
CONCLUSION
Our results demonstrate that metabolic syndrome and migraine headache had not significant correlation; however, higher body mass index and waist circumference as metabolic syndrome components had correlated with migraine headache.
背景
先前的一些研究评估了代谢综合征与偏头痛之间的相关性。然而，尚无研究比较有偏头痛和无偏头痛患者的代谢综合征患病率。控制诸如代谢综合征等并存因素可降低偏头痛患者的治疗抵抗性。本研究的目的是比较有偏头痛和无偏头痛患者的代谢综合征患病率。
材料与方法
本研究纳入了200例根据国际头痛协会诊断的偏头痛患者和200例无偏头痛的健康对照者。根据ATP III标准在这两组中诊断代谢综合征并进行相互比较。
结果
在本研究中，17%（34例）的偏头痛患者和15%（30例）无偏头痛的健康对照者患有代谢综合征。（P = 0.585）。在代谢综合征组分中，偏头痛患者的体重指数（P = 0.05）和腰围（P = 0.03）明显更常见。
结论
我们的结果表明，代谢综合征与偏头痛无显著相关性；然而，作为代谢综合征组分的较高体重指数和腰围与偏头痛相关。
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