Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Department of Maxillofacial Biomedical Engineering, Kyung Hee University, Seoul, S.Korea.
Comput Struct Biotechnol J. 2013 Sep 21;7:e201304005. doi: 10.5936/csbj.201304005. eCollection 2013.
Recently, a wide range of nanotechnologies has been approached for material modification by realizing the fact that the extracellular matrix (ECM) consists of nanoscale components and exhibits nanoscale architectures. Moreover, cell-cell and cell- ECM interactions actively occur on the nanoscale and ultimately play large roles in determining cell fate in tissue engineering. Nanomaterials have provided the potential to preferentially control the behavior and differentiation of cells. The present paper reviews the need for nanotechnology in regenerative medicine and the role of nanotechnology in repairing, restoring, and regenerating damaged body parts, such as blood vessels, lungs, and the heart.
最近，通过认识到细胞外基质（ECM）由纳米级成分组成并表现出纳米级结构这一事实，广泛的纳米技术已被应用于材料改性。此外，细胞-细胞和细胞-ECM 相互作用在纳米尺度上积极发生，并最终在组织工程中对决定细胞命运起着重要作用。纳米材料提供了优先控制细胞行为和分化的潜力。本文综述了再生医学中纳米技术的必要性以及纳米技术在修复、恢复和再生受损身体部位（如血管、肺和心脏）方面的作用。
