3D生物电子界面：通过化学和拓扑控制将循环肿瘤细胞捕获到基于导电聚合物的微/纳米棒阵列上。
3D bioelectronic interface: capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control.
作者信息
Hsiao Yu-Sheng, Luo Shyh-Chyang, Hou Shuang, Zhu Bo, Sekine Jun, Kuo Chiung-Wen, Chueh Di-Yen, Yu Hsiao-Hua, Tseng Hsian-Rong, Chen Peilin
机构信息
Department of Materials Engineering, Ming Chi University of Technology, 84 Gunjuan Road, Taishan, New Taipei City, 24301, Taiwan; Research Center for Applied Sciences, Academia Sinica, Taipei, 11529, Taiwan.
出版信息
Small. 2014 Aug 13;10(15):3012-7. doi: 10.1002/smll.201400429. Epub 2014 Apr 3.
Abstract
The three-dimensional (3D) poly(3,4-ethylenedioxythiophene) (PEDOT)-based bioelectronic interfaces (BEIs) with diverse dimensional micro/nanorod array structures, varied surface chemical pro-perties, high electrical conductivity, reversible chemical redox switching, and high optical transparency are used for capturing circulating tumor cells (CTCs). Such 3D PEDOT-based BEIs can function as an efficient clinical diagonstic and therapeutic platform.
摘要
具有多种尺寸的微/纳米棒阵列结构、不同的表面化学性质、高电导率、可逆化学氧化还原切换以及高光学透明度的基于三维（3D）聚（3,4-乙撑二氧噻吩）（PEDOT）的生物电子界面（BEIs）被用于捕获循环肿瘤细胞（CTC）。这种基于3D PEDOT的BEIs可作为一个高效的临床诊断和治疗平台。
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