• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

3D生物电子界面：通过化学和拓扑控制将循环肿瘤细胞捕获到基于导电聚合物的微/纳米棒阵列上。

3D bioelectronic interface: capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control.

作者信息

Hsiao Yu-Sheng, Luo Shyh-Chyang, Hou Shuang, Zhu Bo, Sekine Jun, Kuo Chiung-Wen, Chueh Di-Yen, Yu Hsiao-Hua, Tseng Hsian-Rong, Chen Peilin

机构信息

Department of Materials Engineering, Ming Chi University of Technology, 84 Gunjuan Road, Taishan, New Taipei City, 24301, Taiwan; Research Center for Applied Sciences, Academia Sinica, Taipei, 11529, Taiwan.

出版信息

Small. 2014 Aug 13;10(15):3012-7. doi: 10.1002/smll.201400429. Epub 2014 Apr 3.

DOI:10.1002/smll.201400429
PMID:24700425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4125486/
Abstract

The three-dimensional (3D) poly(3,4-ethylenedioxythiophene) (PEDOT)-based bioelectronic interfaces (BEIs) with diverse dimensional micro/nanorod array structures, varied surface chemical pro-perties, high electrical conductivity, reversible chemical redox switching, and high optical transparency are used for capturing circulating tumor cells (CTCs). Such 3D PEDOT-based BEIs can function as an efficient clinical diagonstic and therapeutic platform.

摘要

具有多种尺寸的微/纳米棒阵列结构、不同的表面化学性质、高电导率、可逆化学氧化还原切换以及高光学透明度的基于三维（3D）聚（3,4-乙撑二氧噻吩）（PEDOT）的生物电子界面（BEIs）被用于捕获循环肿瘤细胞（CTC）。这种基于3D PEDOT的BEIs可作为一个高效的临床诊断和治疗平台。

相似文献

1
3D bioelectronic interface: capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control.3D生物电子界面：通过化学和拓扑控制将循环肿瘤细胞捕获到基于导电聚合物的微/纳米棒阵列上。
Small. 2014 Aug 13;10(15):3012-7. doi: 10.1002/smll.201400429. Epub 2014 Apr 3.
2
Poly(3,4-ethylenedioxythiophene)-Based Nanofiber Mats as an Organic Bioelectronic Platform for Programming Multiple Capture/Release Cycles of Circulating Tumor Cells.基于聚（3,4-亚乙基二氧噻吩）的纳米纤维垫作为一种有机生物电子平台，用于编程循环肿瘤细胞的多次捕获/释放。
ACS Appl Mater Interfaces. 2017 Sep 13;9(36):30329-30342. doi: 10.1021/acsami.7b07042. Epub 2017 Sep 1.
3
3D printing of highly conductive and strongly adhesive PEDOT:PSS hydrogel-based bioelectronic interface for accurate electromyography monitoring.基于 3D 打印的高导电性和强附着力 PEDOT:PSS 水凝胶生物电子接口，用于准确的肌电图监测。
J Colloid Interface Sci. 2025 Jan;677(Pt A):198-207. doi: 10.1016/j.jcis.2024.05.171. Epub 2024 May 23.
4
Enhanced catalytic and dopamine sensing properties of electrochemically reduced conducting polymer nanocomposite doped with pure graphene oxide.电化学还原掺杂纯氧化石墨烯的导电聚合物纳米复合材料的催化性能和多巴胺传感性能增强。
Biosens Bioelectron. 2014 Aug 15;58:153-6. doi: 10.1016/j.bios.2014.02.055. Epub 2014 Mar 1.
5
Multidimensional conducting polymer nanotubes for ultrasensitive chemical nerve agent sensing.多维导电聚合物纳米管用于超灵敏化学神经毒剂感测。
Nano Lett. 2012 Jun 13;12(6):2797-802. doi: 10.1021/nl204587t. Epub 2012 May 2.
6
Facile Fabrication of Microwrinkled Poly(3,4-Ethylenedioxythiophene) Films that Promote Neural Differentiation under Electrical Stimulation.在电刺激下促进神经分化的微皱纹聚（3,4-亚乙基二氧噻吩）薄膜的简易制备。
ACS Appl Bio Mater. 2021 Mar 15;4(3):2354-2362. doi: 10.1021/acsabm.0c01204. Epub 2021 Feb 23.
7
Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection.聚糖刺激可实现基于 PEDOT 纳米魔术贴芯片的前列腺癌循环肿瘤细胞的纯化，从而用于 RNA 生物标志物检测。
Adv Healthc Mater. 2018 Feb;7(3). doi: 10.1002/adhm.201700701. Epub 2017 Sep 11.
8
Uniform thin films of poly-3,4-ethylenedioxythiophene (PEDOT) prepared by in-situ deposition.通过原位沉积制备的聚3,4-乙撑二氧噻吩（PEDOT）均匀薄膜。
Chem Commun (Camb). 2001 Dec 7(23):2444-5. doi: 10.1039/b107130k.
9
Experimental and theoretical characterization of implantable neural microelectrodes modified with conducting polymer nanotubes.用导电聚合物纳米管修饰的可植入神经微电极的实验与理论表征
Biomaterials. 2008 Mar;29(9):1273-83. doi: 10.1016/j.biomaterials.2007.11.022.
10
Nanostructured poly(3,4-ethylenedioxythiophene)-metalloporphyrin films: improved catalytic detection of peroxynitrite.纳米结构聚(3,4-亚乙基二氧噻吩)-金属卟啉薄膜：改善过氧亚硝酸盐的催化检测。
Biosens Bioelectron. 2010 Apr 15;25(8):1914-21. doi: 10.1016/j.bios.2010.01.008. Epub 2010 Jan 20.

引用本文的文献

1
Versatile Organic Electrochemical Transistors with Self-Assembled Coronene Nanofiber Arrays for the Isolation and Detection of Circulating Tumor Cells and Enhanced Secretion of Extracellular Vesicles.具有自组装并四苯纳米纤维阵列的多功能有机电化学晶体管用于循环肿瘤细胞的分离与检测及细胞外囊泡分泌增强
ACS Appl Mater Interfaces. 2025 Jun 11;17(23):33592-33605. doi: 10.1021/acsami.5c05442. Epub 2025 May 30.
2
Poly(3,4-ethylenedioxythiophene) Nanorod Arrays-Based Organic Electrochemical Transistor for SARS-CoV-2 Spike Protein Detection in Artificial Saliva.基于聚（3,4-乙撑二氧噻吩）纳米棒阵列的有机电化学晶体管用于人工唾液中SARS-CoV-2刺突蛋白的检测
ACS Sens. 2025 Mar 28;10(3):2007-2018. doi: 10.1021/acssensors.4c03207. Epub 2025 Mar 13.
3

本文引用的文献

1
A conducting-polymer platform with biodegradable fibers for stimulation and guidance of axonal growth.一种具有生物可降解纤维的导电聚合物平台，用于刺激和引导轴突生长。
Adv Mater. 2009 Nov 20;21(43):4393-7. doi: 10.1002/adma.200901165. Epub 2009 Aug 20.
2
Highly Aligned Poly(3,4-ethylene dioxythiophene) (PEDOT) Nano- and Microscale Fibers and Tubes.高度取向的聚（3,4-乙撑二氧噻吩）（PEDOT）纳米和微米级纤维及管
Polymer (Guildf). 2013 Jan 24;54(2):702-708. doi: 10.1016/j.polymer.2012.10.057.
3
Tuning of cell-biomaterial anchorage for tissue regeneration.
Easy-to-Engineer Flexible Nanoelectrode Sensor from an Inexpensive Overhead Projector Sheet for Sweat Neuropeptide-Y Detection.一种基于廉价投影仪胶片的易于制造的柔性纳米电极传感器，用于检测汗液中的神经肽Y。
ACS Appl Bio Mater. 2024 Dec 16;7(12):8423-8433. doi: 10.1021/acsabm.4c01229. Epub 2024 Nov 16.
4
Conducting polymer-based sensors for food and drug analysis.基于导电聚合物的食品和药物分析传感器。
J Food Drug Anal. 2021 Dec 15;29(4):544-558. doi: 10.38212/2224-6614.3374.
5
Nanomaterial-Based Immunocapture Platforms for the Recognition, Isolation, and Detection of Circulating Tumor Cells.基于纳米材料的免疫捕获平台用于循环肿瘤细胞的识别、分离和检测
Front Bioeng Biotechnol. 2022 Mar 14;10:850241. doi: 10.3389/fbioe.2022.850241. eCollection 2022.
6
Micro/Nanopatterned Superhydrophobic Surfaces Fabrication for Biomolecules and Biomaterials Manipulation and Analysis.用于生物分子和生物材料操控与分析的微/纳米图案化超疏水表面制备
Micromachines (Basel). 2021 Nov 30;12(12):1501. doi: 10.3390/mi12121501.
7
Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips.利用纳米基底嵌入微芯片发现和描述神经内分泌肿瘤患者的循环肿瘤细胞簇。
Biosens Bioelectron. 2022 Mar 1;199:113854. doi: 10.1016/j.bios.2021.113854. Epub 2021 Dec 3.
8
On the Interaction between 1D Materials and Living Cells.一维材料与活细胞之间的相互作用
J Funct Biomater. 2020 Jun 10;11(2):40. doi: 10.3390/jfb11020040.
9
Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications.用于检测和表征循环稀有细胞的纳米结构基底：从材料研究到临床应用。
Adv Mater. 2020 Jan;32(1):e1903663. doi: 10.1002/adma.201903663. Epub 2019 Sep 30.
10
Random and aligned electrospun PLGA nanofibers embedded in microfluidic chips for cancer cell isolation and integration with air foam technology for cell release.随机取向的电纺 PLGA 纳米纤维嵌入微流控芯片中，用于癌细胞分离，并与气泡沫技术结合用于细胞释放。
J Nanobiotechnology. 2019 Feb 19;17(1):31. doi: 10.1186/s12951-019-0466-2.
细胞-生物材料锚定的组织再生调节。
Adv Mater. 2013 Aug 7;25(29):4049-57. doi: 10.1002/adma.201301227.
4
Direct measurement of ion mobility in a conducting polymer.直接测量导电聚合物中的离子迁移率。
Adv Mater. 2013 Aug 27;25(32):4488-93. doi: 10.1002/adma.201301240. Epub 2013 Jun 20.
5
Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells.用于单个循环黑色素瘤细胞检测、分离和分子分析的聚合物纳米纤维嵌入微芯片。
Angew Chem Int Ed Engl. 2013 Mar 18;52(12):3379-83. doi: 10.1002/anie.201208452. Epub 2013 Feb 21.
6
Materiomics: an -omics approach to biomaterials research.物质组学：一种用于生物材料研究的组学方法。
Adv Mater. 2013 Feb 13;25(6):802-24. doi: 10.1002/adma.201202553. Epub 2013 Jan 7.
7
Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures.聚合物接枝硅纳米结构上循环肿瘤细胞的捕获和刺激释放。
Adv Mater. 2013 Mar 20;25(11):1547-51. doi: 10.1002/adma.201203185. Epub 2012 Dec 17.
8
Stem-cell niche based comparative analysis of chemical and nano-mechanical material properties impacting ex vivo expansion and differentiation of hematopoietic and mesenchymal stem cells.基于干细胞龛的比较分析：化学和纳米力学材料特性对造血和间充质干细胞体外扩增和分化的影响。
Adv Healthc Mater. 2013 Jan;2(1):25-42. doi: 10.1002/adhm.201200169. Epub 2012 Sep 17.
9
Electrically tunable organic bioelectronics for spatial and temporal manipulation of neuron-like pheochromocytoma (PC-12) cells.用于对神经元样嗜铬细胞瘤（PC-12）细胞进行时空操纵的电可调有机生物电子学。
Biochim Biophys Acta. 2013 Sep;1830(9):4321-8. doi: 10.1016/j.bbagen.2012.08.028. Epub 2012 Sep 12.
10
Substrate dependent stability of conducting polymer coatings on medical electrodes.在医用电极上，基于基底的导电聚合物涂层的稳定性。
Biomaterials. 2012 Sep;33(25):5875-86. doi: 10.1016/j.biomaterials.2012.05.017. Epub 2012 May 30.