Sahin Alparslan, Sahin Muhammed, Türkcü Fatih Mehmet, Cingü Abdullah Kürşat, Yüksel Harun, Cınar Yasin, Arı Seyhmus, Caça Ihsan
Department of Ophthalmology, School of Medicine, Dicle University, Diyarbakır, Turkey.
ISRN Pediatr. 2014 Mar 9;2014:134347. doi: 10.1155/2014/134347. eCollection 2014.
Purpose. To investigate the incidence and the severity of retinopathy of prematurity (ROP) in extremely preterm infants born before 28 weeks of gestation in southeastern Turkey. Methods. A retrospective chart review was performed for infants born before 28 weeks of gestation. The following data were reviewed: gender, gestational age (GA), birth weight (BW), zone and stage of ROP, presence of plus disease, and treatment for ROP if needed. Infants were divided into 2 groups according to GA as follows: group 1 included infants of GAs 25 weeks and under; group 2 included infants of GAs less than 28 weeks and over 25 weeks. Results. The incidence of any ROP in the whole cohort, in group 1, and in group 2, was 66.0%, 95.5%, and 58.6%, respectively. Incidence of any ROP was significantly associated with BW and GA (P = 0.014 and P = 0.002, resp.). The overall incidence of type 1 ROP was 35.8% (59.1% in group 1 and 29.9% in group 2). Development of type 1 ROP was independently associated with GA. Conclusion. Any ROP was significantly associated with BW and GA. Extremely premature infants with lower GA were found to be more likely to develop type 1 ROP. BW cannot predict the development of type 1 ROP.
目的。调查土耳其东南部妊娠28周前出生的极早产儿中早产儿视网膜病变（ROP）的发病率及严重程度。方法。对妊娠28周前出生的婴儿进行回顾性病历审查。审查了以下数据：性别、胎龄（GA）、出生体重（BW）、ROP的区域和阶段、是否存在Plus病以及必要时ROP的治疗情况。根据胎龄将婴儿分为两组：第1组包括胎龄25周及以下的婴儿；第2组包括胎龄小于28周且大于25周的婴儿。结果。整个队列、第1组和第2组中任何ROP的发病率分别为66.0%、95.5%和58.6%。任何ROP的发病率与BW和GA均显著相关（分别为P = 0.014和P = 0.002）。1型ROP的总体发病率为35.8%（第1组为59.1%，第2组为29.9%）。1型ROP的发生与GA独立相关。结论。任何ROP均与BW和GA显著相关。发现胎龄较低的极早产儿更易发生1型ROP。BW无法预测1型ROP的发生。
