埃及草药山地唇萼薄荷的化学成分及其抗菌和抗真菌活性。
Chemical constituents and their antibacterial and antifungal activity from the Egyptian herbal medicine Chiliadenus montanus.
作者信息
Hegazy Mohamed-Elamir F, Matsuda Hisashi, Nakamura Seikou, Hussein Taha A, Yoshikawa Masayuki, Paré Paul W
机构信息
Chemistry of Medicinal Plants Department, and Center of Excellence for Advanced Sciences, National Research Centre, El-Tahrir St., Dokki, Giza 12622, Egypt.
Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan.
出版信息
Phytochemistry. 2014 Jul;103:154-161. doi: 10.1016/j.phytochem.2014.03.027. Epub 2014 Apr 17.
Phytochemical investigations of the CH2Cl2/MeOH (1:1) extract of air-dried aerial parts of Chiliadenus montanus afforded eight metabolites, in addition to eight other previously reported compounds, of which two were isolated for the first time as free acids. Structures were established by spectroscopic methods, including HREIMS, (1)H, (13)C, DEPT, (1)H-(1)H COSY, HMQC and HMBC NMR analysis. Antimicrobial activity against an array of common bacterial and fungal strains was measured via a colorimetric assay with minimal growth inhibition observed in the μg/mL range for one of the tested metabolites.
对山地千屈菜风干地上部分的二氯甲烷/甲醇（1:1）提取物进行植物化学研究，除了其他八种先前报道的化合物外，还得到了八种代谢产物，其中两种首次作为游离酸被分离出来。通过高分辨电子轰击质谱（HREIMS）、氢谱（¹H）、碳谱（¹³C）、无畸变极化转移增强谱（DEPT）、氢-氢化学位移相关谱（¹H-¹H COSY）、异核单量子相干谱（HMQC）和异核多键相关谱（HMBC）核磁共振分析等光谱方法确定了其结构。通过比色法测定了对一系列常见细菌和真菌菌株的抗菌活性，在所测试的一种代谢产物中，在微克/毫升范围内观察到最小的生长抑制。
Zotero 插件