Repin Mikhail, Turner Helen C, Garty Guy, Brenner David J
Center for High-Throughput Minimally Invasive Radiation Biodosimetry, Columbia University Medical Center, New York, NY 10032, USA
Center for High-Throughput Minimally Invasive Radiation Biodosimetry, Columbia University Medical Center, New York, NY 10032, USA.
Radiat Prot Dosimetry. 2014 Jun;159(1-4):105-10. doi: 10.1093/rpd/ncu161. Epub 2014 May 17.
Here the general concept of the combined use of plates and tubes in racks compatible with the American National Standards Institute/the Society for Laboratory Automation and Screening microplate formats as the next generation platforms for increasing the throughput of biodosimetry assays was described. These platforms can be used at different stages of biodosimetry assays starting from blood collection into microtubes organised in standardised racks and ending with the cytogenetic analysis of samples in standardised multiwell and multichannel plates. Robotically friendly platforms can be used for different biodosimetry assays in minimally equipped laboratories and on cost-effective automated universal biotech systems.
本文描述了在与美国国家标准学会/实验室自动化与筛选协会微孔板格式兼容的架子中使用板和管的组合的一般概念,作为提高生物剂量测定分析通量的下一代平台。这些平台可用于生物剂量测定分析的不同阶段,从将血液收集到标准化架子中的微量管开始,到对标准化多孔板和多通道板中的样品进行细胞遗传学分析结束。对机器人友好的平台可用于设备配备最少的实验室中的不同生物剂量测定分析,以及具有成本效益的自动化通用生物技术系统。