Int J Prosthodont. 2014 May-Jun;27(3):215-25. doi: 10.11607/ijp.3759.
To assess the effect of chemical disinfection procedures on the surface roughness of hard denture base materials.
A systematic literature review was conducted using five electronic databases (Medline, Cochrane Library, OpenGrey, Lilac, and Google Scholar) along with hand searching of the bibliographies of all located articles.
The review yielded 193 articles. This number was reduced to 25 by using defined inclusion and exclusion criteria. Only one in vivo study was included; all others were in vitro evaluations. For every disinfecting agent, studies were found that reported surface alteration after chemical disinfection. The current literature suggests that changes in roughness might be more often associated with sodium perborate (three out of three studies with positive correlation) and less often with chlorhexidine digluconate and glutaraldehyde (two out of seven and one out of four studies with positive correlation, respectively). Because only single studies were found for glycine-type amphoteric surfactant solution, enzyme solution, ethanol, berberine hydrochloride, chlorine, reactive oxygen species, peracetic acid, cetylpyridinium chloride, and citric acid, no conclusions can be drawn about these disinfectants.
Physical surface alteration is only one aspect when deciding on the use of chemical disinfection procedures. More research is needed to clarify whether these procedures can be recommended to patients.
评估化学消毒程序对硬质义齿基托材料表面粗糙度的影响。
通过使用 5 个电子数据库（Medline、Cochrane 图书馆、OpenGrey、Lilac 和 Google Scholar）以及对所有定位文章的参考文献进行手工搜索，进行了系统的文献回顾。
综述共产生了 193 篇文章。通过使用定义的纳入和排除标准，这一数字减少到 25 篇。仅纳入了一项体内研究；所有其他研究均为体外评估。对于每种消毒剂，都有研究报告称化学消毒后表面发生了改变。目前的文献表明，粗糙度的变化可能更常与过硼酸钠（三项研究均呈正相关）相关，而与洗必泰葡萄糖酸盐和戊二醛相关性较小（分别有两项和一项研究呈正相关）。由于仅对甘氨酸型两性表面活性剂溶液、酶溶液、乙醇、盐酸小檗碱、氯、活性氧、过氧乙酸、十六烷基吡啶氯和柠檬酸进行了单项研究，因此无法对这些消毒剂得出结论。
在决定使用化学消毒程序时，物理表面改变只是一个方面。需要进一步的研究来阐明这些程序是否可以推荐给患者。
