Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Locked Bag 10, Parkville, Melbourne, Victoria 3052, Australia ; Centre of Excellence in Youth Mental Health, headspace National Youth Mental Health Foundation Ltd, Level 2, South Tower, 485 La Trobe Street, Melbourne, Victoria 3000, Australia.
Melbourne School of Population Health, The University of Melbourne, Level 3, 207 Bouverie Street, Melbourne, Victoria 3010, Australia.
J Eat Disord. 2014 Feb 3;2:5. doi: 10.1186/2050-2974-2-5. eCollection 2014.
Eating disorders often develop during adolescence and young adulthood, and are associated with significant psychological and physical burden. Identifying evidence-based interventions is critical and there is need to take stock of the extant literature, to inform clinical practice regarding well-researched interventions and to direct future research agendas by identifying gaps in the evidence base.
To investigate and quantify the nature and distribution of existing high-quality research on the prevention and treatment of eating disorders in young people using evidence mapping methodology.
A systematic search for prevention and treatment intervention studies in adolescents and young adults (12-25 years) was conducted using EMBASE, PSYCINFO and MEDLINE. Studies were screened and mapped according to disorder, intervention modality, stage of eating disorder and study design. Included studies were restricted to controlled trials and systematic reviews published since 1980.
The eating disorders evidence map included 197 trials and 22 systematic reviews. Prevention research was dominated by trials of psychoeducation (PE). Bulimia nervosa (BN) received the most attention in the treatment literature, with cognitive behavioural therapy (CBT) and antidepressants the most common interventions. For anorexia nervosa (AN), family based therapy (FBT) was the most studied. Lacking were trials exploring treatments for binge eating disorder (BED) and eating disorder not otherwise specified (EDNOS). Relapse prevention strategies were notably absent across the eating disorders.
Despite substantial literature devoted to the prevention and treatment of eating disorders in young people, the evidence base is not well established and significant gaps remain. For those identified as being at-risk, there is need for prevention research exploring strategies other than passive PE. Treatment interventions targeting BED and EDNOS are required, as are systematic reviews synthesising BN treatment trials (e.g., CBT, antidepressants). FBTs for AN require investigation against other validated psychological interventions, and the development of relapse prevention strategies is urgently required. By systematically identifying existing interventions for young people with eating disorders and exposing gaps in the current literature, the evidence map can inform researchers, funding bodies and policy makers as to the opportunities for future research.
饮食失调症常发生于青少年和青年时期,与显著的心理和生理负担有关。确定基于证据的干预措施至关重要,需要对现有文献进行评估,为针对研究充分的干预措施的临床实践提供信息,并通过确定证据基础中的差距来指导未来的研究议程。
采用证据图谱方法,调查和量化年轻人饮食失调症预防和治疗方面现有高质量研究的性质和分布。
通过 EMBASE、PSYCINFO 和 MEDLINE 系统地检索针对青少年和青年(12-25 岁)的预防和治疗干预研究。根据障碍、干预方式、饮食失调阶段和研究设计对研究进行筛选和图谱绘制。纳入的研究限于自 1980 年以来发表的对照试验和系统评价。
饮食失调症证据图谱包括 197 项试验和 22 项系统评价。预防研究主要集中于心理教育(PE)试验。在治疗文献中,神经性贪食症(BN)受到最多关注,最常见的干预措施是认知行为疗法(CBT)和抗抑郁药。针对神经性厌食症(AN),家庭为基础的治疗(FBT)是研究最多的。缺乏针对暴食障碍(BED)和未特定饮食失调症(EDNOS)的治疗试验。在所有饮食失调症中,预防复发的策略明显缺失。
尽管有大量文献致力于研究年轻人的饮食失调症预防和治疗,但证据基础并不完善,仍存在重大差距。对于那些被确定为有风险的人,需要探索除被动 PE 以外的预防策略。需要针对 BED 和 EDNOS 进行治疗干预,还需要对 BN 治疗试验(如 CBT、抗抑郁药)进行系统评价。需要对针对 AN 的 FBT 进行其他经证实的心理干预的研究,并迫切需要制定预防复发的策略。通过系统地确定针对患有饮食失调症的年轻人的现有干预措施,并揭示当前文献中的差距,证据图谱可以为研究人员、资助机构和决策者提供未来研究的机会。