一种用于选择性检测细胞内过氧亚硝酸盐的基于硼酸盐的荧光探针。
A boronate-based fluorescent probe for the selective detection of cellular peroxynitrite.
作者信息
Kim Jiyoung, Park Jeesook, Lee Hawon, Choi Yongdoo, Kim Youngmi
机构信息
Department of Chemistry, Institute of Nanosensor and Biotechnology, Dankook University, 152 Jukjeon-ro, Suji-gu, Yongin-si, Gyeonggi-do 448-701, Korea.
出版信息
Chem Commun (Camb). 2014 Aug 25;50(66):9353-6. doi: 10.1039/c4cc02943g.
A boronate-based fluorescent probe 1 for the selective monitoring of intracellular peroxynitrite has been developed. The probe takes advantage of the fast reaction of an arylboronate group with peroxynitrite, yielding a corresponding phenol that undergoes spontaneous subsequent reactions to produce a strongly fluorescent product associated with a large turn-on signal.
一种用于选择性监测细胞内过氧亚硝酸盐的基于硼酸酯的荧光探针1已被开发出来。该探针利用芳基硼酸酯基团与过氧亚硝酸盐的快速反应，生成相应的苯酚，该苯酚会自发地进行后续反应，产生一种与大的开启信号相关的强荧光产物。
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