Liu Bin, Liu Jikui, Wang Guoqing, Huang Kun, Li Fan, Zheng Yang, Luo Youxi, Zhou Fengfeng
Cardiovascular Disease Center, First Hospital of Jilin University, Changchun 130021, Jilin, PR China.
Shenzhen Institutes of Advanced Technology, and Key Lab for Health Informatics, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, PR China.
Comput Biol Med. 2015 Jun;61:178-84. doi: 10.1016/j.compbiomed.2014.08.010. Epub 2014 Aug 20.
The electrocardiogram (ECG) is a biophysical electric signal generated by the heart muscle, and is one of the major measurements of how well a heart functions. Automatic ECG analysis algorithms usually extract the geometric or frequency-domain features of the ECG signals and have already significantly facilitated automatic ECG-based cardiac disease diagnosis. We propose a novel ECG feature by fitting a given ECG signal with a 20th order polynomial function, defined as PolyECG-S. The PolyECG-S feature is almost identical to the fitted ECG curve, measured by the Akaike information criterion (AIC), and achieved a 94.4% accuracy in detecting the Myocardial Infarction (MI) on the test dataset. Currently ST segment elongation is one of the major ways to detect MI (ST-elevation myocardial infarction, STEMI). However, many ECG signals have weak or even undetectable ST segments. Since PolyECG-S does not rely on the information of ST waves, it can be used as a complementary MI detection algorithm with the STEMI strategy. Overall, our results suggest that the PolyECG-S feature may satisfactorily reconstruct the fitted ECG curve, and is complementary to the existing ECG features for automatic cardiac function analysis.
心电图(ECG)是由心肌产生的生物物理电信号,是衡量心脏功能好坏的主要指标之一。自动心电图分析算法通常提取心电图信号的几何或频域特征,并且已经显著促进了基于心电图的心脏病自动诊断。我们通过用20阶多项式函数拟合给定的心电图信号,提出了一种新的心电图特征,定义为PolyECG-S。通过赤池信息准则(AIC)测量,PolyECG-S特征几乎与拟合的心电图曲线相同,并且在测试数据集上检测心肌梗死(MI)时达到了94.4%的准确率。目前,ST段延长是检测MI(ST段抬高型心肌梗死,STEMI)的主要方法之一。然而,许多心电图信号的ST段微弱甚至无法检测到。由于PolyECG-S不依赖于ST波的信息,它可以作为STEMI策略的一种补充MI检测算法。总体而言,我们的结果表明,PolyECG-S特征可以令人满意地重建拟合的心电图曲线,并且对于自动心脏功能分析与现有的心电图特征互补。