Grosso Giuseppe, Stepaniak Urszula, Topor-Mądry Roman, Szafraniec Krystyna, Pająk Andrzej
Department of Clinical and Molecular Biomedicine, Section of Pharmacology and Biochemistry, University of Catania, Catania, Italy; Department of Epidemiology and Population Studies, Jagiellonian University Medical College, Krakow, Poland.
Department of Epidemiology and Population Studies, Jagiellonian University Medical College, Krakow, Poland.
Nutrition. 2014 Nov-Dec;30(11-12):1398-403. doi: 10.1016/j.nut.2014.04.012. Epub 2014 May 9.
The aim of this study was to estimate the intake of known individual polyphenols and their major dietary sources in the Polish arm of the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study.
A total of 10,477 random sample (45-69 y) of urban population of Krakow, Poland, completed a validated 148-item food frequency questionnaire. Polyphenol intake was calculated by matching food consumption data with the recently developed Phenol-Explorer database.
The mean intake of polyphenols was 1756.5 ± 695.8 mg/d (median = 1662.5 mg/d). The main polyphenol groups were flavonoids (897 mg/d) and phenolic acids (800 mg/d). A total of 347 polyphenols from 19 polyphenol subclasses were found. The individual compounds with the highest intakes were isomers of chlorogenic acid (i.e., 5-caffeoylquinic acid and 4-caffeoylquinic acid) among hydroxycinnamic acids (average intake 150 mg/d), that largely originated from coffee, and compounds belonging to the catechin chemical family (i.e., [+]-gallocatechin, [-]-epigallocatechin 3-O-gallate, and [-]-epicatechin) among flavanols (average intake 50 mg/d), that mostly originated from tea and cocoa products.
The current study provides the most updated data for individual polyphenols intake in the diet of a well-established nutritional cohort. These findings will be useful to assess potential beneficial role on health of specific foods with high polyphenol content and characterize the effects of individual phenolic compounds.
本研究旨在评估健康、酒精和社会心理因素在东欧(HAPIEE)研究波兰分支中已知的个体多酚摄入量及其主要膳食来源。
波兰克拉科夫城市人口的10477名随机样本(45 - 69岁)完成了一份经过验证的148项食物频率问卷。通过将食物消费数据与最近开发的酚类物质探索者数据库进行匹配来计算多酚摄入量。
多酚的平均摄入量为1756.5±695.8毫克/天(中位数 = 1662.5毫克/天)。主要的多酚类群是黄酮类化合物(897毫克/天)和酚酸(800毫克/天)。共发现了来自19个多酚亚类的347种多酚。摄入量最高的个体化合物是羟基肉桂酸中的绿原酸异构体(即5 - 咖啡酰奎尼酸和4 - 咖啡酰奎尼酸)(平均摄入量150毫克/天),其主要来源于咖啡,以及黄烷醇中的儿茶素化学家族化合物(即[+] - 没食子儿茶素、[-] - 表没食子儿茶素3 - O - 没食子酸酯和[-] - 表儿茶素)(平均摄入量50毫克/天),其大多来源于茶和可可制品。
本研究为一个成熟营养队列饮食中个体多酚摄入量提供了最新数据。这些发现将有助于评估高多酚含量特定食物对健康的潜在有益作用,并描述个体酚类化合物的影响。