Mori M, VAN Esbroeck M, Depoorter S, Decaluwe W, Vandecasteele S J, Fretin D, Reynders M
Veterinary and Agrochemical Research Centre, CODA-CERVA,Brussels,Belgium.
Tropical Medicine Institute, ITM,Antwerp,Belgium.
Epidemiol Infect. 2015 Jun;143(8):1761-6. doi: 10.1017/S0950268814002763. Epub 2014 Oct 14.
An outbreak of leptospirosis occurred in the South of Belgium, during August 2012, in teenagers who participated in two consecutive adventure scout camps near the Semois river. Among the symptomatic patient population (ten scouts), clinical manifestations included headache (70%), myalgia (50%), fever (50%), bilateral conjunctival injection (50%), general malaise (30%), vomiting (20%), anorexia (20%) and cough (20%). Some of the cases presented elevated blood creatinine (40%), or proteinuria (30%). Three patients were confirmed by serology and one by polymerase chain reaction. Potential risk factors included direct contact with a muskrat and indirect contact with potentially contaminated environments including the river water. Prospective environmental investigation carried out near the river banks 2 weeks after the outbreak identified Ondatra zibethicus (muskrat) as one Leptospira sp. reservoir.
2012年8月,比利时南部发生了一起钩端螺旋体病疫情,疫情发生在参加了位于塞穆瓦河附近连续两个探险童子军营地活动的青少年中。在有症状的患者群体(10名童子军)中,临床表现包括头痛(70%)、肌痛(50%)、发热(50%)、双侧结膜充血(50%)、全身不适(30%)、呕吐(20%)、厌食(20%)和咳嗽(20%)。部分病例出现血肌酐升高(40%)或蛋白尿(30%)。3例患者通过血清学确诊,1例通过聚合酶链反应确诊。潜在危险因素包括直接接触麝鼠以及间接接触包括河水在内的潜在污染环境。疫情爆发两周后在河岸附近进行的前瞻性环境调查确定北美麝鼠为一种钩端螺旋体菌的宿主。