Amidi Salimeh, Mojab Faraz, Bayandori Moghaddam Abdolmajid, Tabib Kimia, Kobarfard Farzad
Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran J Pharm Res. 2012 Winter;11(1):117-21.
Clinical and Epidemiological studies have shown that a diet rich in fruits and vegetables is associated with a decreased risk of cardiovascular diseases, cancers and other related disorders. These beneficial health effects have been attributed in part to the presence of antioxidants in dietary plants. Therefore screening for antioxidant properties of plant extracts has been one of the interests of scientists in this field. Different screening methods have been reported for the evaluation of antioxidant properties of plant extracts in the literature. In the present research a rapid screening method has been introduced based on cyclic voltammetry for antioxidant screening of some selected medicinal plant extracts. CYCLIC VOLTAMMETRY OF METHANOLIC EXTRACTS OF SEVEN MEDICINAL PLANTS: Buxus hyrcana, Rumex crispus, Achillea millefolium, Zataria multiflora, Ginkgo biloba, Lippia citriodora and Heptaptera anisoptera was carried out at different scan rates. Based on the interpretation of voltammograms, Rumex crispus, Achillea millefolium and Ginkgo biloba showed higher antioxidant capability than the others while Lippia citriodora contained the highest amount of antioxidants. Cyclic voltammetry is expected to be a simple method for screening antioxidants and estimating the antioxidant activity of foods and medicinal plants.
临床和流行病学研究表明，富含水果和蔬菜的饮食与心血管疾病、癌症及其他相关疾病风险降低有关。这些有益的健康效应部分归因于膳食植物中存在抗氧化剂。因此，筛选植物提取物的抗氧化特性一直是该领域科学家的兴趣之一。文献中已报道了不同的筛选方法用于评估植物提取物的抗氧化特性。在本研究中，基于循环伏安法引入了一种快速筛选方法，用于对一些选定药用植物提取物进行抗氧化筛选。对七种药用植物（布克苏铁线莲、皱叶酸模、千叶蓍、多花百里香、银杏、柠檬马鞭草和异翅七鳃鳗）的甲醇提取物进行了不同扫描速率下的循环伏安法测定。根据伏安图的解释，皱叶酸模、千叶蓍和银杏显示出比其他植物更高的抗氧化能力，而柠檬马鞭草含有最高量的抗氧化剂。循环伏安法有望成为一种筛选抗氧化剂以及估计食品和药用植物抗氧化活性的简单方法。
