Sgorbini M, Bonelli F, Marmorini P, Biagi G, Corazza M, Pasquini A
Department of Veterinary Sciences, University of Pisa, Pisa, Italy.
Theriogenology. 2015 Jan 1;83(1):48-51. doi: 10.1016/j.theriogenology.2014.07.041.
The aim of the present work was to evaluate derivated reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) in mares and foals to study perinatal oxidative status. A total of 60 animals were included in the present study. Maternal and foal venous blood samples were collected immediately after delivery along with a sample drawn from one of the umbilical arteries, and plasma samples were evaluated for lactatemia, d-ROMs, and BAP. The t test for unpaired data was applied between mares versus umbilical artery blood versus foals, both for d-ROMs and BAP. The Pearson test with two-tailed P value and a confidence interval of 95% was performed between d-ROMs and BAP and between d-ROMs and lactatemia, both for mares and foals. Finally, the t test for unpaired data was performed between fillies and colts. The t test showed differences between mares versus their own foals versus umbilical artery blood but not foals versus. umbilical artery blood, both for d-ROMs and BAP. A positive correlation was found both in mares and foals between BAP and d-ROMs and in mares between lactatemia and d-ROM. No differences in gender were found in BAP concentration. Our data are in line to previous studies performed in women and cattle.
本研究的目的是评估母马和马驹体内的衍生活性氧代谢产物（d-ROMs）和生物抗氧化潜力（BAP），以研究围产期的氧化状态。本研究共纳入60只动物。分娩后立即采集母马和马驹的静脉血样本以及脐动脉之一的血样，并对血浆样本进行乳酸血症、d-ROMs和BAP评估。对母马、脐动脉血和马驹的d-ROMs和BAP均采用非配对数据t检验。对母马和马驹的d-ROMs与BAP之间以及d-ROMs与乳酸血症之间进行双侧P值和95%置信区间的Pearson检验。最后，对小母马和小公马进行非配对数据t检验。t检验显示，在d-ROMs和BAP方面，母马与其自身的马驹以及脐动脉血之间存在差异，但马驹与脐动脉血之间无差异。在母马和马驹中，BAP与d-ROMs之间以及在母马中乳酸血症与d-ROM之间均发现正相关。在BAP浓度方面未发现性别差异。我们的数据与之前在女性和牛身上进行的研究一致。
