Shono Saori, Gin Azusa, Minowa Fumiko, Okubo Kimihiro, Mochizuki Mariko
Department of Applied Science, School of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University, Tokyo 180-8602, Japan.
Minowa Horse Clinic, Tokyo 144-0033, Japan.
Animals (Basel). 2020 Apr 3;10(4):617. doi: 10.3390/ani10040617.
Diacron-reactive oxygen metabolite (d-ROM) and biological antioxidant potential (BAP) levels in the serum of horses were measured (ponies, = 15; thoroughbred, = 31; other full-sized horses, = 7). The mean d-ROM levels in horses were significantly higher ( < 0.001) than those in dairy cattle ( = 25) and dogs ( = 31). However, d-ROM levels in horses were lower than the standard levels reported in humans. When d-ROM and BAP levels were plotted graphically, the points for horses with a disease (ringbone in 1 Japanese sports horse, cellulitis in 1 thoroughbred, melanoma in 1 Lipizzaner) fell outside the group of points for other (non-diseased) horses. A similar separation was seen (using data from other authors) for a horse with , a horse following castration surgery, and a mare following delivery. These results, comparing horses, other animals, and humans, are interesting from the standpoint of comparative medicine, and they contribute to the sparse literature available on d-ROM and BAP levels in animals. Because the level of d-ROM and BAP levels were changed depending on the situation of health, those indexes are promising as indices of health in horses.
测量了马匹血清中的Diacron活性氧代谢产物（d-ROM）和生物抗氧化潜力（BAP）水平（矮种马，n = 15；纯种马，n = 31；其他成年马，n = 7）。马匹的平均d-ROM水平显著高于奶牛（n = 25）和犬类（n = 31）（P < 0.001）。然而，马匹的d-ROM水平低于人类报告的标准水平。当以图形方式绘制d-ROM和BAP水平时，患有疾病的马匹（1匹日本运动马患环骨瘤、1匹纯种马患蜂窝织炎、1匹利皮扎马患黑色素瘤）的点落在其他（无疾病）马匹的点组之外。对于一匹患有[疾病名称未给出]的马、一匹阉割手术后的马和一匹分娩后的母马，也观察到了类似的分离情况（使用其他作者的数据）。从比较医学的角度来看，这些比较马匹、其他动物和人类的结果很有趣，并且它们为关于动物d-ROM和BAP水平的稀少文献做出了贡献。由于d-ROM和BAP水平会根据健康状况而变化，因此这些指标有望作为马匹健康的指标。
