Griffith Lauren E, van den Heuvel Edwin, Fortier Isabel, Sohel Nazmul, Hofer Scott M, Payette Hélène, Wolfson Christina, Belleville Sylvie, Kenny Meghan, Doiron Dany, Raina Parminder
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
Department of Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, The Netherlands.
J Clin Epidemiol. 2015 Feb;68(2):154-62. doi: 10.1016/j.jclinepi.2014.09.003. Epub 2014 Dec 8.
To identify statistical methods for harmonization, the procedures aimed at achieving the comparability of previously collected data, which could be used in the context of summary data and individual participant data meta-analysis of cognitive measures.
Environmental scan methods were used to conduct two reviews to identify (1) studies that quantitatively combined data on cognition and (2) general literature on statistical methods for data harmonization. Search results were rapidly screened to identify articles of relevance.
All 33 meta-analyses combining cognition measures either restricted their analyses to a subset of studies using a common measure or combined standardized effect sizes across studies; none reported their harmonization steps before producing summary effects. In the second scan, three general classes of statistical harmonization models were identified (1) standardization methods, (2) latent variable models, and (3) multiple imputation models; few publications compared methods.
Although it is an implicit part of conducting a meta-analysis or pooled analysis, the methods used to assess inferential equivalence of complex constructs are rarely reported or discussed. Progress in this area will be supported by guidelines for the conduct and reporting of the data harmonization and integration and by evaluating and developing statistical approaches to harmonization.
确定用于数据协调的统计方法，即旨在使先前收集的数据具有可比性的程序，这些方法可用于认知测量的汇总数据和个体参与者数据的荟萃分析。
采用环境扫描方法进行两项综述，以确定（1）对认知数据进行定量合并的研究，以及（2）关于数据协调统计方法的一般文献。对搜索结果进行快速筛选以确定相关文章。
所有33项合并认知测量的荟萃分析，要么将分析限制在使用共同测量方法的研究子集中，要么合并了不同研究的标准化效应量；在得出汇总效应之前，均未报告其协调步骤。在第二次扫描中，确定了三类统计协调模型：（1）标准化方法，（2）潜在变量模型，以及（3）多重插补模型；很少有出版物对这些方法进行比较。
尽管评估复杂结构的推断等效性所使用的方法是进行荟萃分析或汇总分析的一个隐含部分，但很少有报告或讨论。该领域的进展将得到数据协调与整合的实施和报告指南以及评估和开发协调统计方法的支持。
