Liu Shuo, Wall Thomas A, Ozcelik Damla, Parks Joshua W, Hawkins Aaron R, Schmidt Holger
School of Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Chem Commun (Camb). 2015 Feb 7;51(11):2084-7. doi: 10.1039/c4cc07591a.
Single λ-DNA molecules are detected on a nanopore-gated optofluidic chip electrically and optically. Statistical variations in the single particle trajectories are used to predict the intensity distribution of the fluorescence signals.
在纳米孔门控光流体芯片上通过电学和光学方法检测单个λ-DNA分子。利用单个粒子轨迹的统计变化来预测荧光信号的强度分布。