Department of General Psychology, University of Padova Padova, Italy ; Human Inspired Technologies Research Centre, University of Padova Padova, Italy.
Department of General Psychology, University of Padova Padova, Italy.
Front Psychol. 2014 Dec 9;5:1402. doi: 10.3389/fpsyg.2014.01402. eCollection 2014.
Amblyopia is a visual disorder due to an abnormal pattern of functional connectivity of the visual cortex and characterized by several visual deficits of spatial vision including impairments of visual acuity (VA) and of the contrast sensitivity function (CSF). Despite being a developmental disorder caused by reduced visual stimulation during early life (critical period), several studies have shown that extensive visual perceptual training can improve VA and CSF in people with amblyopia even in adulthood. With the present study we assessed whether a much shorter perceptual training regime, in association with high-frequency transcranial electrical stimulation (hf-tRNS), was able to improve visual functions in a group of adult participants with amblyopia. Results show that, in comparison with previous studies where a large number sessions with a similar training regime were used (Polat et al., 2004), here just eight sessions of training in contrast detection under lateral masking conditions combined with hf-tRNS, were able to substantially improve VA and CSF in adults with amblyopia.
弱视是一种视觉障碍，源于视觉皮层功能连接异常，其特点是存在多种空间视觉缺陷，包括视力（VA）和对比敏感度功能（CSF）受损。尽管弱视是一种由生命早期（关键期）视觉刺激减少引起的发育障碍，但多项研究表明，广泛的视觉感知训练可以改善弱视患者的 VA 和 CSF，即使在成年后也是如此。在本研究中，我们评估了一种更短的感知训练方案，结合高频经颅电刺激（hf-tRNS），是否能够改善一组成年弱视患者的视觉功能。结果表明，与之前使用大量相似训练方案的研究相比（Polat 等人，2004 年），在这里，仅仅在侧抑制条件下进行八次对比检测训练，结合 hf-tRNS，就能够显著改善成年弱视患者的 VA 和 CSF。
