Lerner Chad A, Sundar Isaac K, Watson Richard M, Elder Alison, Jones Ryan, Done Douglas, Kurtzman Rachel, Ossip Deborah J, Robinson Risa, McIntosh Scott, Rahman Irfan
Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, NY 14642, USA.
Environ Pollut. 2015 Mar;198:100-7. doi: 10.1016/j.envpol.2014.12.033. Epub 2015 Jan 9.
To narrow the gap in our understanding of potential oxidative properties associated with Electronic Nicotine Delivery Systems (ENDS) i.e. e-cigarettes, we employed semi-quantitative methods to detect oxidant reactivity in disposable components of ENDS/e-cigarettes (batteries and cartomizers) using a fluorescein indicator. These components exhibit oxidants/reactive oxygen species reactivity similar to used conventional cigarette filters. Oxidants/reactive oxygen species reactivity in e-cigarette aerosols was also similar to oxidant reactivity in cigarette smoke. A cascade particle impactor allowed sieving of a range of particle size distributions between 0.450 and 2.02 μm in aerosols from an e-cigarette. Copper, being among these particles, is 6.1 times higher per puff than reported previously for conventional cigarette smoke. The detection of a potentially cytotoxic metal as well as oxidants from e-cigarette and its components raises concern regarding the safety of e-cigarettes use and the disposal of e-cigarette waste products into the environment.
为缩小我们对电子尼古丁传送系统（ENDS）即电子烟潜在氧化特性理解上的差距，我们采用半定量方法，使用荧光素指示剂检测ENDS/电子烟（电池和雾化器）一次性组件中的氧化剂反应活性。这些组件展现出的氧化剂/活性氧物质反应活性与用过的传统香烟滤嘴相似。电子烟烟雾中的氧化剂/活性氧物质反应活性也与香烟烟雾中的氧化剂反应活性相似。一种级联式颗粒冲击器能够筛选出电子烟烟雾中粒径在0.450至2.02μm之间的一系列颗粒分布。铜就在这些颗粒之中，每口烟雾中的含量比之前报道的传统香烟烟雾高出6.1倍。电子烟及其组件中潜在细胞毒性金属以及氧化剂的检测引发了对电子烟使用安全性以及将电子烟废弃物排放到环境中的担忧。
